Christopher W Lawrence
Overview
Explore the profile of Christopher W Lawrence including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
730
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Recent Articles
1.
Lawrence C
DNA Repair (Amst)
. 2007 Jan;
6(5):676-86.
PMID: 17254849
Errol Friedberg suggested that I write a biographical account of the work carried out in my lab for the Historical Reflections section of the DNA Repair. Although I started out...
2.
Zhang H, Gibbs P, Lawrence C
Genetics
. 2006 Jun;
173(4):1983-9.
PMID: 16783012
The rev6-1 allele was isolated in a screen for mutants deficient for UV-induced reversion of the frameshift mutation his4-38. Preliminary testing showed that the rev6-1 mutant was substantially deficient for...
3.
Zhang H, Lawrence C
Proc Natl Acad Sci U S A
. 2005 Oct;
102(44):15954-9.
PMID: 16247017
Evidence for an error-free DNA damage tolerance process in eukaryotes (also called postreplication repair) has existed for more than two decades, but its underlying mechanism, although known to be different...
4.
Drake 3rd D, Ream R, Lawrence C, Braciale T
J Immunol
. 2005 Jul;
175(3):1507-15.
PMID: 16034088
Engagement of the Ag receptor on naive CD8+ T cells by specific peptide-MHC complex triggers their activation/expansion/differentiation into effector CTL. The frequency of Ag-specific CD8+ T cells can normally be...
5.
Hoffman P, Wang H, Lawrence C, Iwai S, Hanaoka F, Hays J
DNA Repair (Amst)
. 2005 Jul;
4(9):983-93.
PMID: 15996534
Mismatch-repair (MMR) systems suppress mutation via correction of DNA replication errors (base-mispairs) and responses to mutagenic DNA lesions. Selective binding of mismatched or damaged DNA by MutS-homolog proteins-bacterial MutS, eukaryotic...
6.
Lawrence C, Ream R, Braciale T
J Immunol
. 2005 Apr;
174(9):5332-40.
PMID: 15843530
We have used intracellular cytokine staining and MHC class I tetramer binding in conjunction with granzyme B protease expression and in vivo BrdU uptake to characterize the primary murine CD8(+)...
7.
Ozgenc A, Szekeres E, Lawrence C
J Bacteriol
. 2005 Mar;
187(6):1974-84.
PMID: 15743945
We have investigated recombination mechanisms promoting the completion of replication in the face of unrepaired DNA damage by transforming an isogenic set of uvrA6 excision-defective Escherichia coli strains with pUC-based...
8.
9.
Gibbs P, McDonald J, Woodgate R, Lawrence C
Genetics
. 2004 Nov;
169(2):575-82.
PMID: 15520252
We have investigated the relative roles in vivo of Saccharomyces cerevisiae DNA polymerase eta, DNA polymerase zeta, Rev1 protein, and the DNA polymerase delta subunit, Pol32, in the bypass of...
10.
Lawrence C, Braciale T
J Immunol
. 2004 Jul;
173(2):1209-18.
PMID: 15240712
The low precursor frequency of individual virus-specific CD8(+) T cells in a naive host makes the early events of CD8(+) T cell activation, proliferation, and differentiation in response to viral...