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Christopher Schroeder

Explore the profile of Christopher Schroeder including associated specialties, affiliations and a list of published articles. Areas
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Articles 61
Citations 922
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Recent Articles
1.
Clasen K, Ballin N, Schutz L, Bonzheim I, Kelemen O, Orth M, et al.
Clin Transl Radiat Oncol . 2024 Dec; 50:100894. PMID: 39670057
Background And Purpose: Neoadjuvant chemoradiotherapy (NCRT) is a standard treatment option for locally advanced rectal cancer. However, there is still conflicting data about the genetic landscape and potential dynamics during...
2.
Clasen K, Gani C, Schuetz L, Clasen S, Ballin N, Bonzheim I, et al.
Radiat Oncol . 2024 Nov; 19(1):153. PMID: 39506775
Background: In locally advanced rectal cancer, the prediction of tumor response during and after neoadjuvant treatment remains challenging. In terms of organ preservation, adaptive radiotherapy, and intensified (total) neoadjuvant therapies,...
3.
Schroeder C, Gatidis S, Kelemen O, Schutz L, Bonzheim I, Muyas F, et al.
Nat Commun . 2024 Oct; 15(1):8750. PMID: 39384805
Immune checkpoint inhibitors (ICI) have significantly improved overall survival in melanoma patients. However, 60% experience severe adverse events and early response markers are lacking. Circulating tumour DNA (ctDNA) is a...
4.
Menzel M, Martis-Thiele M, Goldschmid H, Ott A, Romanovsky E, Siemanowski-Hrach J, et al.
Eur J Cancer . 2024 Sep; 211:114306. PMID: 39293347
Introduction: Whole Exome Sequencing (WES) has emerged as an efficient tool in clinical cancer diagnostics to broaden the scope from panel-based diagnostics to screening of all genes and enabling robust...
5.
Forchhammer S, Pop O, Hahn M, Aebischer V, Seitz C, Schroeder C, et al.
Virchows Arch . 2024 Jun; 485(2):335-346. PMID: 38890171
Tumor-associated antigens (TAAs) are potential targets for T cell-based immunotherapy approaches in cutaneous melanoma. BNT111, an investigational lipoplex-formulated mRNA-based therapeutic cancer vaccine encoding melanoma TAAs NY-ESO-1, tyrosinase, MAGE-A3, and TPTE,...
6.
Forchhammer S, Aebischer V, Lenders D, Seitz C, Schroeder C, Liebmann A, et al.
Pigment Cell Melanoma Res . 2024 Mar; 37(4):453-461. PMID: 38509752
Pediatric melanomas are rare tumors that have clinical and histological differences from adult melanomas. In adult melanoma, the immunohistochemical marker PRAME is increasingly employed as a diagnostic adjunct. PRAME is...
7.
Riess O, Sturm M, Menden B, Liebmann A, Demidov G, Witt D, et al.
NPJ Genom Med . 2024 Mar; 9(1):20. PMID: 38485733
In the era of precision medicine, genome sequencing (GS) has become more affordable and the importance of genomics and multi-omics in clinical care is increasingly being recognized. However, how to...
8.
Menzel M, Ossowski S, Kral S, Metzger P, Horak P, Marienfeld R, et al.
NPJ Precis Oncol . 2023 Oct; 7(1):106. PMID: 37864096
A growing number of druggable targets and national initiatives for precision oncology necessitate broad genomic profiling for many cancer patients. Whole exome sequencing (WES) offers unbiased analysis of the entire...
9.
Abdel-Salam G, Hellmuth S, Gradhand E, Kaseberg S, Winter J, Pabst A, et al.
JCI Insight . 2023 Oct; 8(22). PMID: 37796616
MAD2L1BP-encoded p31comet mediates Trip13-dependent disassembly of Mad2- and Rev7-containing complexes and, through this antagonism, promotes timely spindle assembly checkpoint (SAC) silencing, faithful chromosome segregation, insulin signaling, and homology-directed repair (HDR)...
10.
Liebmann A, Admard J, Armeanu-Ebinger S, Wild H, Abele M, Gschwind A, et al.
EBioMedicine . 2023 Sep; 96:104797. PMID: 37716236
Background: Genomic characterisation has led to an improved understanding of adult melanoma. However, the aetiology of melanoma in children is still unclear and identifying the correct diagnosis and therapeutic strategies...