Christopher S Freet
Overview
Explore the profile of Christopher S Freet including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
149
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0
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Recent Articles
1.
Freet C, Evans B, Brick T, Deneke E, Wasserman E, Ballard S, et al.
Addict Sci Clin Pract
. 2024 Jul;
19(1):56.
PMID: 39061093
Background: Despite continuing advancements in treatments for opioid use disorder (OUD), continued high rates of relapse indicate the need for more effective approaches, including novel pharmacological interventions. Glucagon-like peptide 1...
2.
Petrie D, Knapp K, Freet C, Deneke E, Brick T, Cleveland H, et al.
Brain Res Bull
. 2022 Sep;
190:32-41.
PMID: 36122801
Both anhedonia and craving are common among patients with opioid use disorder (OUD), and are associated with vulnerability to relapse. Although these constructs are theoretically linked relatively few studies have...
3.
Evans B, Stoltzfus B, Acharya N, Nyland J, Arnold A, Freet C, et al.
Brain Res Bull
. 2022 Aug;
189:163-173.
PMID: 36038016
Opioid use disorder (OUD), like other substance use disorders (SUDs), is widely understood to be a disorder of persistent relapse. Despite the use of three FDA-approved medications for OUD, typically...
4.
Yang T, Choi C, Walter F, Freet C, Liang N
Nutr Neurosci
. 2021 Oct;
25(12):2547-2559.
PMID: 34633918
Objectives: There is a clear association between obesity and impulsivity. While exercise can suppress weight gain and decrease impulsive choice (IC), the relationship between impulsivity, the consumption of palatable, energy...
5.
Mukherjee D, Stankoski D, Tilden S, Huhn A, Bixler E, Kong L, et al.
Drug Alcohol Depend
. 2021 Aug;
227:108931.
PMID: 34392049
Objective: Research has demonstrated that hypothalamic-pituitary-adrenal (HPA) axis function and sleep patterns are dysregulated in patients diagnosed with opioid use disorder (OUD). It is unclear whether and/or when cortisol and...
6.
Bao L, Festa F, Freet C, Lee J, Hirschler-Laszkiewicz I, Chen S, et al.
Sci Rep
. 2019 Oct;
9(1):14132.
PMID: 31575956
Transient receptor potential melastatin channel subfamily member 2 (TRPM2) has an essential role in protecting cell viability through modulation of oxidative stress. TRPM2 is highly expressed in cancer. When TRPM2...
7.
Freet C, Alexander D, Imperio C, Ruiz-Velasco V, Grigson P
Brain Res Bull
. 2017 Sep;
138:73-79.
PMID: 28939474
The single nucleotide polymorphism of the μ-opioid receptor, OPRM1 A118G, has been associated with greater drug and alcohol use, increased sensitivity to pain, and reduced sensitivity to the antinociceptive effects...
8.
Twining R, Freet C, Wheeler R, Reich C, Tompers D, Wolpert S, et al.
Physiol Behav
. 2016 Apr;
161:104-115.
PMID: 27083122
Rats avoid intake of a taste cue when paired with a drug of abuse or with the illness-inducing agent, lithium chloride (LiCl). Although progress has been made, it is difficult...
9.
Biegler J, Freet C, Horvath N, Rogers A, Hajnal A
Brain Res Bull
. 2015 Aug;
123:47-52.
PMID: 26304761
Roux-en-Y gastric bypass (RYGB) surgery is a commonly performed and very effective method to achieve significant, long-term weight loss. Opioid analgesics are primarily used to manage postoperative pain as fewer...
10.
Freet C, Lawrence A
Physiol Behav
. 2015 Jun;
149:174-80.
PMID: 26066719
Growing evidence implicates glutamate homeostasis in a number of behaviors observed in addiction such as acquisition of drug taking, motivation, and reinstatement. To date, however, the role of glutamate homeostasis...