Christopher Rathnam
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Explore the profile of Christopher Rathnam including associated specialties, affiliations and a list of published articles.
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Articles
14
Citations
157
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Recent Articles
1.
Yang L, Rathnam C, Hidaka T, Hou Y, Conklin B, Pandian G, et al.
Nano Lett
. 2023 Jan;
23(5):2046-2055.
PMID: 36688839
The growing knowledge of the links between aberrant mitochondrial gene transcription and human diseases necessitates both an effective and dynamic approach to control mitochondrial DNA (mtDNA) transcription. To address this...
2.
Li Y, Biswas R, Kopcha W, Dubroca T, Abella L, Sun Y, et al.
Angew Chem Int Ed Engl
. 2022 Nov;
62(3):e202211704.
PMID: 36349405
Endohedral metallofullerenes (EMFs) are excellent carriers of rare-earth element (REE) ions in biomedical applications because they preclude the release of toxic metal ions. However, existing approaches to synthesize water-soluble EMF...
3.
Yang L, Conley B, Yoon J, Rathnam C, Pongkulapa T, Conklin B, et al.
Research (Wash D C)
. 2022 Oct;
2022:9784273.
PMID: 36204248
A systematic investigation of stem cell-derived neural interfaces can facilitate the discovery of the molecular mechanisms behind cell behavior in neurological disorders and accelerate the development of stem cell-based therapies....
4.
Luo J, Yang L, Chueng S, Conley B, Rathnam C, Lee K
ACS Appl Mater Interfaces
. 2022 Jul;
14(30):34488-34501.
PMID: 35862271
Seamlessly integrating soluble factors onto biomedical scaffolds with a precisely manufactured topography for efficient cell control remains elusive since many scaffold fabrication techniques degrade payloads. Surface adsorption of payloads onto...
5.
Yang L, Conley B, Rathnam C, Cho H, Pongkulapa T, Conklin B, et al.
ACS Nano
. 2022 Mar;
16(4):5577-5586.
PMID: 35301847
Biophysical cues, such as nanotopographies of extracellular matrix (ECM), are key cell regulators for direct cell reprogramming. Therefore, high-throughput methods capable of systematically screening a wide range of biophysical cue-regulated...
6.
Yang L, Patel K, Rathnam C, Thangam R, Hou Y, Kang H, et al.
Small
. 2022 Feb;
18(13):e2104783.
PMID: 35132796
Extracellular vesicles (e.g., exosomes) carrying various biomolecules (e.g., proteins, lipids, and nucleic acids) have rapidly emerged as promising platforms for many biomedical applications. Despite their enormous potential, their heterogeneity in...
7.
Rathnam C, Yang L, Castro-Pedrido S, Luo J, Cai L, Lee K
Sci Adv
. 2021 Sep;
7(40):eabj2281.
PMID: 34586845
Although stem cell therapy holds enormous potential for treating debilitating injuries and diseases in the central nervous system, low survival and inefficient differentiation have restricted its clinical applications. Recently, 3D...
8.
Yi S, Zhang Y, Rathnam C, Pongkulapa T, Lee K
Adv Mater
. 2021 Sep;
33(45):e2007949.
PMID: 34561899
Recent advances in 3D cell culture technology have enabled scientists to generate stem cell derived organoids that recapitulate the structural and functional characteristics of native organs. Current organoid technologies have...
9.
Rathnam C, Chueng S, Ying Y, Lee K, Kwan K
Front Cell Neurosci
. 2019 Nov;
13:493.
PMID: 31780898
Sensorineural hearing loss affects millions of people worldwide and is a growing concern in the aging population. Treatment using aminoglycoside antibiotics for infection and exposure to loud sounds contribute to...
10.
Yang L, Lee J, Rathnam C, Hou Y, Choi J, Lee K
Nano Lett
. 2019 Oct;
19(11):8138-8148.
PMID: 31663759
Surface-enhanced Raman scattering (SERS) has demonstrated great potential to analyze a variety of bio/chemical molecular interactions within cells in a highly sensitive and selective manner. Despite significant advancements, it remains...