Christopher R W Edwards
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Explore the profile of Christopher R W Edwards including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
189
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Recent Articles
1.
Timoshenko R, Gorelkin P, Vaneev A, Krasnovskaya O, Akasov R, Garanina A, et al.
Anal Chem
. 2023 Dec;
96(1):127-136.
PMID: 38126724
In vitro/in vivo detection of copper ions is a challenging task but one which is important in the development of new approaches to the diagnosis and treatment of cancer and...
2.
Kolmogorov V, Erofeev A, Barykin E, Timoshenko R, Lopatukhina E, Kozin S, et al.
Anal Chem
. 2023 Oct;
95(43):15943-15949.
PMID: 37856787
β-Amyloid aggregation on living cell surfaces is described as responsible for the neurotoxicity associated with different neurodegenerative diseases. It is suggested that the aggregation of β-amyloid (Aβ) peptide on neuronal...
3.
Woodcock E, Gorelkin P, Goff P, Edwards C, Zhang Y, Korchev Y, et al.
Cells
. 2023 Oct;
12(19).
PMID: 37830615
A cell's mechanical properties have been linked to cancer development, motility and metastasis and are therefore an attractive target as a universal, reliable cancer marker. For example, it has been...
4.
Vaneev A, Gorelkin P, Krasnovskaya O, Akasov R, Spector D, Lopatukhina E, et al.
Anal Chem
. 2022 Mar;
94(12):4901-4905.
PMID: 35285614
The biodistribution of chemotherapy compounds within tumor tissue is one of the main challenges in the development of antineoplastic drugs, and techniques for simple, inexpensive, sensitive, and selective detection of...
5.
Kolmogorov V, Erofeev A, Woodcock E, Efremov Y, Iakovlev A, Savin N, et al.
Nanoscale
. 2021 Apr;
13(13):6558-6568.
PMID: 33885535
Mechanical properties of living cells determined by cytoskeletal elements play a crucial role in a wide range of biological functions. However, low-stress mapping of mechanical properties with nanoscale resolution but...
6.
Vaneev A, Gorelkin P, Garanina A, Lopatukhina H, Vodopyanov S, Alova A, et al.
Anal Chem
. 2020 May;
92(12):8010-8014.
PMID: 32441506
monitoring of reactive oxygen species (ROS) in tumors during treatment with anticancer therapy is important for understanding the mechanism of action and in the design of new anticancer drugs. In...
7.
Palomino-Doza J, Rahman T, Avery P, Mayosi B, Farrall M, Watkins H, et al.
Hypertension
. 2008 Oct;
52(5):980-5.
PMID: 18852390
The P2X receptor gene family encodes a series of proteins that function as ATP-gated nonselective ion channels. P2X receptor channels are involved in transducing aldosterone-mediated signaling in the distal renal...
8.
Gorelik J, Zhang Y, Shevchuk A, Frolenkov G, Sanchez D, Lab M, et al.
Mol Cell Endocrinol
. 2004 May;
217(1-2):101-8.
PMID: 15134807
Background: Continuous high spatial resolution observations of living A6 cells would greatly aid the elucidation of the relationship between structure and function and facilitate the study of major physiological processes...
9.
Lavery G, Ronconi V, Draper N, Rabbitt E, Lyons V, Chapman K, et al.
Hypertension
. 2003 Jul;
42(2):123-9.
PMID: 12860834
Mutations in the gene encoding 11beta-hydroxysteroid dehydrogenase type 2, 11beta-HSD2 (HSD11B2), explain the molecular basis for the syndrome of apparent mineralocorticoid excess (AME), characterized by severe hypertension and hypokalemic alkalosis....
10.
Gorelik J, Shevchuk A, Frolenkov G, Diakonov I, Lab M, Kros C, et al.
Proc Natl Acad Sci U S A
. 2003 May;
100(10):5819-22.
PMID: 12721367
Although the dynamics of cell membranes and associated structures is vital for cell function, little is known due to lack of suitable methods. We found, using scanning ion conductance microscopy,...