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Christopher Petucci

Explore the profile of Christopher Petucci including associated specialties, affiliations and a list of published articles. Areas
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Articles 23
Citations 724
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Recent Articles
1.
Sule R, Hu P, Shoffler C, Petucci C, Wilkins B, Rychik J, et al.
J Am Heart Assoc . 2025 Mar; :e039201. PMID: 40055870
Background: The Fontan operation is the current standard of care for single-ventricle congenital heart disease. Almost all patients with Fontan operation develop liver fibrosis at a young age, known as...
2.
Chourasia S, Petucci C, Shoffler C, Abbasian D, Wang H, Han X, et al.
EMBO J . 2025 Jan; 44(4):1007-1038. PMID: 39753955
Mitochondrial carrier homolog 2 (MTCH2) is a regulator of apoptosis, mitochondrial dynamics, and metabolism. Loss of MTCH2 results in mitochondrial fragmentation, an increase in whole-body energy utilization, and protection against...
3.
Tamburro M, Bonilla K, Shetye S, Leahy T, Eekhoff J, Kim M, et al.
J Orthop Res . 2024 Dec; 43(3):519-530. PMID: 39731286
Exercise influences clinical Achilles tendon health in humans, but animal models of exercise-related Achilles tendon changes are lacking. Moreover, previous investigations of the effects of treadmill running exercise on rat...
4.
Naeem F, Leone T, Petucci C, Shoffler C, Kodihalli R, Hidalgo T, et al.
medRxiv . 2024 Aug; PMID: 39108509
Background: Two general phenotypes of heart failure (HF) are recognized: HF with reduced ejection fraction (HFrEF) and with preserved EF (HFpEF). To develop HF disease phenotype-specific approaches to define and...
5.
Wong A, Devason A, Umana I, Cox T, Dohnalova L, Litichevskiy L, et al.
Cell . 2023 Oct; 186(22):4851-4867.e20. PMID: 37848036
Post-acute sequelae of COVID-19 (PASC, "Long COVID") pose a significant global health challenge. The pathophysiology is unknown, and no effective treatments have been found to date. Several hypotheses have been...
6.
Lundgren P, Sharma P, Dohnalova L, Coleman K, Uhr G, Kircher S, et al.
Nat Metab . 2023 Oct; 5(10):1691-1705. PMID: 37783943
Sustained responses to transient environmental stimuli are important for survival. The mechanisms underlying long-term adaptations to temporary shifts in abiotic factors remain incompletely understood. Here, we find that transient cold...
7.
Hahn V, Petucci C, Kim M, Bedi Jr K, Wang H, Mishra S, et al.
Circulation . 2023 Mar; 147(15):1147-1161. PMID: 36856044
Background: The human heart primarily metabolizes fatty acids, and this decreases as alternative fuel use rises in heart failure with reduced ejection fraction (HFrEF). Patients with severe obesity and diabetes...
8.
Lund P, Gates L, Leboeuf M, Smith S, Chau L, Lopes M, et al.
Cell Rep . 2022 Dec; 41(11):111809. PMID: 36516747
The gut microbiota influences acetylation on host histones by fermenting dietary fiber into butyrate. Although butyrate could promote histone acetylation by inhibiting histone deacetylases, it may also undergo oxidation to...
9.
Previs M, OLeary T, Morley M, Palmer B, LeWinter M, Yob J, et al.
Circ Heart Fail . 2022 May; 15(6):e009521. PMID: 35543134
Background: Defects in energetics are thought to be central to the pathophysiology of hypertrophic cardiomyopathy (HCM); yet, the determinants of ATP availability are not known. The purpose of this study...
10.
Schultz D, Johnson R, Ayyanathan K, Miller J, Whig K, Kamalia B, et al.
Nature . 2022 Feb; 604(7904):134-140. PMID: 35130559
The SARS-CoV-2 virus has infected more than 261 million people and has led to more than 5 million deaths in the past year and a half ( https://www.who.org/ ). Individuals...