Christopher N Foley
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Explore the profile of Christopher N Foley including associated specialties, affiliations and a list of published articles.
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19
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2188
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Recent Articles
1.
Hillary R, Gadd D, Kuncheva Z, Mangelis T, Lin T, Ferber K, et al.
Nat Commun
. 2024 Aug;
15(1):7346.
PMID: 39187491
Understanding how gene-environment interactions (GEIs) influence the circulating proteome could aid in biomarker discovery and validation. The presence of GEIs can be inferred from single nucleotide polymorphisms that associate with...
2.
Gadd D, Hillary R, Kuncheva Z, Mangelis T, Cheng Y, Dissanayake M, et al.
Nat Aging
. 2024 Jul;
4(7):939-948.
PMID: 38987645
The circulating proteome offers insights into the biological pathways that underlie disease. Here, we test relationships between 1,468 Olink protein levels and the incidence of 23 age-related diseases and mortality...
3.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature
. 2023 Feb;
615(7952):E19.
PMID: 36829046
No abstract available.
4.
Kurki M, Karjalainen J, Palta P, Sipila T, Kristiansson K, Donner K, et al.
Nature
. 2023 Jan;
613(7944):508-518.
PMID: 36653562
Population isolates such as those in Finland benefit genetic research because deleterious alleles are often concentrated on a small number of low-frequency variants (0.1% ≤ minor allele frequency < 5%)....
5.
Sun B, Loomis S, Pizzagalli F, Shatokhina N, Painter J, Foley C, et al.
Nat Commun
. 2022 Oct;
13(1):6071.
PMID: 36241887
Genetic associations with macroscopic brain structure can provide insights into brain function and disease. However, specific associations with measures of local brain folding are largely under-explored. Here, we conducted large-scale...
6.
Sun B, Kurki M, Foley C, Mechakra A, Chen C, Marshall E, et al.
Nature
. 2022 Feb;
603(7899):95-102.
PMID: 35197637
Genome-wide association studies (GWAS) have identified thousands of genetic variants linked to the risk of human disease. However, GWAS have so far remained largely underpowered in relation to identifying associations...
7.
Bowker N, Hansford R, Burgess S, Foley C, Auyeung V, Erzurumluoglu A, et al.
Diabetes
. 2021 Aug;
70(11):2706-2719.
PMID: 34426508
There is considerable interest in GIPR agonism to enhance the insulinotropic and extrapancreatic effects of GIP, thereby improving glycemic and weight control in type 2 diabetes (T2D) and obesity. Recent...
8.
Surendran P, Feofanova E, Lahrouchi N, Ntalla I, Karthikeyan S, Cook J, et al.
Nat Genet
. 2021 Mar;
53(5):762.
PMID: 33727701
No abstract available.
9.
Foley C, Staley J, Breen P, Sun B, Kirk P, Burgess S, et al.
Nat Commun
. 2021 Feb;
12(1):764.
PMID: 33536417
Genome-wide association studies (GWAS) have identified thousands of genomic regions affecting complex diseases. The next challenge is to elucidate the causal genes and mechanisms involved. One approach is to use...
10.
Broadbent J, Foley C, Grant A, Mason A, Staley J, Burgess S
Wellcome Open Res
. 2021 Jan;
5:252.
PMID: 33381656
The MendelianRandomization package is a software package written for the R software environment that implements methods for Mendelian randomization based on summarized data. In this manuscript, we describe functions that...