Christopher M Weghorst
Overview
Explore the profile of Christopher M Weghorst including associated specialties, affiliations and a list of published articles.
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Articles
41
Citations
526
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0
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Recent Articles
1.
Mrdjen I, Lee J, Weghorst C, Knobloch T
Toxins (Basel)
. 2022 Jul;
14(7).
PMID: 35878222
Exposure to cyanobacterial hepatotoxins has been linked to the promotion and increased incidence of liver cancer in pre-clinical and epidemiologic studies. The family of hepatotoxins, microcystins (MCs), are produced by...
2.
Cosby L, Lee K, Knobloch T, Weghorst C, Winter J
Int J Nanomedicine
. 2020 Oct;
15:8217-8230.
PMID: 33122907
Purpose: Black raspberries (BRBs) and their anthocyanin-rich hydrophilic fractions (BRB-H) have exhibited significant chemopreventative activity across aerodigestive cancers. Lutein, the primary component of the BRB lipophilic fraction (BRB-L), also demonstrates...
3.
Paskett E, Pennell M, Ruffin M, Weghorst C, Lu B, Hade E, et al.
Cancer Prev Res (Phila)
. 2020 Mar;
13(3):223-228.
PMID: 32132116
The Appalachian region experiences higher incidence and mortality due to cervical cancer compared with other regions of the United States. The goal of the Ohio State University Center for Population...
4.
Knobloch T, Peng J, Hade E, Cohn D, Ruffin 4th M, Schiano M, et al.
Cancer Causes Control
. 2019 Aug;
30(10):1087-1100.
PMID: 31435875
Purpose: This study examined targeted genomic variants of transforming growth factor beta (TGFB) signaling in Appalachian women. Appalachian women with cervical cancer were compared to healthy Appalachian counterparts to determine...
5.
Knobloch T, Ryan N, Bruschweiler-Li L, Wang C, Bernier M, Somogyi A, et al.
Metabolites
. 2019 Jul;
9(7).
PMID: 31336728
Oral cancer is a public health problem with an incidence of almost 50,000 and a mortality of 10,000 each year in the USA alone. Black raspberries (BRBs) have been shown...
6.
Tu P, Xue J, Bian X, Chi L, Gao B, Leng J, et al.
Toxicol Appl Pharmacol
. 2019 Jun;
377:114633.
PMID: 31229487
Arsenic in drinking water is a worldwide public health problem due to its pathogenic induction of oxidative stress in various organ systems. Phytochemicals present in polyphenolic-rich fruits such as black...
7.
Mrdjen I, Morse M, Ruch R, Knobloch T, Choudhary S, Weghorst C, et al.
Toxins (Basel)
. 2018 Oct;
10(11).
PMID: 30373283
Microcystin (MC) exposure is an increasing concern because more geographical locations are covered with cyanobacterial blooms as eutrophication and bloom-favoring environmental factors become more prevalent worldwide. Acute MC exposure has...
8.
Tu P, Bian X, Chi L, Gao B, Ru H, Knobloch T, et al.
ACS Omega
. 2018 Oct;
3(9):10927-10937.
PMID: 30288460
Gut microbiome plays an essential role in host health through host-gut microbiota metabolic interactions. Desirable modulation of beneficial gut bacteria, such as , can confer health benefits by altering microbiome-related...
9.
Teegarden M, Knobloch T, Weghorst C, Cooperstone J, Peterson D
Food Funct
. 2018 Jul;
9(9):4593-4601.
PMID: 30022172
Pre-clinical and clinical studies suggest black raspberries (BRBs) may inhibit the development of oral cancer. Lyophilized BRB powder is commonly used in these studies, but processed BRB products are more...
10.
Oghumu S, Casto B, Ahn-Jarvis J, Weghorst L, Maloney J, Geuy P, et al.
Front Immunol
. 2017 Nov;
8:1325.
PMID: 29109723
Oral cancer continues to be a significant public health problem worldwide. Recently conducted clinical trials demonstrate the ability of black raspberries (BRBs) to modulate biomarkers of molecular efficacy that supports...