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Christopher M Mazzone

Explore the profile of Christopher M Mazzone including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 931
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11.
Navarro M, Olney J, Burnham N, Mazzone C, Lowery-Gionta E, Pleil K, et al.
Neuropsychopharmacology . 2015 Oct; 41(6):1505-12. PMID: 26442599
It was recently reported that activation of a subset of lateral hypothalamus (LH) GABAergic neurons induced both appetitive (food-seeking) and consummatory (eating) behaviors in vGat-ires-cre mice, while inhibition or deletion...
12.
Vardy E, Robinson J, Li C, Olsen R, DiBerto J, Giguere P, et al.
Neuron . 2015 May; 86(4):936-946. PMID: 25937170
DREADDs are chemogenetic tools widely used to remotely control cellular signaling, neuronal activity, and behavior. Here we used a structure-based approach to develop a new Gi-coupled DREADD using the kappa-opioid...
13.
Pleil K, Rinker J, Lowery-Gionta E, Mazzone C, McCall N, Kendra A, et al.
Nat Neurosci . 2015 Mar; 18(4):545-52. PMID: 25751534
Binge alcohol drinking is a tremendous public health problem because it leads to the development of numerous pathologies, including alcohol abuse and anxiety. It is thought to do so by...
14.
Mazzone C, LaRese T, Kiraly D, Eipper B, Mains R
Mol Pharmacol . 2012 Sep; 82(6):1241-9. PMID: 22989522
Estradiol treatment of ovariectomized rodents is known to affect the morphology of dendritic spines and produce behavioral and cognitive effects. Kalirin-7 (Kal7), a postsynaptic density (PSD)-localized Rho-guanine nucleotide exchange factor,...
15.
Kiraly D, Ma X, Mazzone C, Xin X, Mains R, Eipper B
Biol Psychiatry . 2010 May; 68(3):249-55. PMID: 20452575
Background: Long-lasting increases in dendritic spine density and gene expression in the nucleus accumbens and in the ambulatory response to cocaine occur following chronic cocaine treatment. Despite numerous reports of...