Christopher M Kirton
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Explore the profile of Christopher M Kirton including associated specialties, affiliations and a list of published articles.
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8
Citations
367
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Recent Articles
1.
Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, et al.
Nature
. 2017 Jun;
546(7660):686.
PMID: 28614302
This corrects the article DOI: 10.1038/nature22403.
2.
Kilpinen H, Goncalves A, Leha A, Afzal V, Alasoo K, Ashford S, et al.
Nature
. 2017 May;
546(7658):370-375.
PMID: 28489815
Technology utilizing human induced pluripotent stem cells (iPS cells) has enormous potential to provide improved cellular models of human disease. However, variable genetic and phenotypic characterization of many existing iPS...
3.
Agu C, Soares F, Alderton A, Patel M, Ansari R, Patel S, et al.
Stem Cell Reports
. 2015 Sep;
5(4):660-71.
PMID: 26388286
The collection sites of human primary tissue samples and the receiving laboratories, where the human induced pluripotent stem cells (hIPSCs) are derived, are often not on the same site. Thus,...
4.
Armour K, Smith C, Ip N, Ellison C, Kirton C, Wilkes A, et al.
PLoS One
. 2014 Oct;
9(10):e109463.
PMID: 25302805
We previously produced a recombinant version of the human anti-RhD antibody Fog-1 in the rat myeloma cell line, YB2/0. When human, autologous RhD-positive red blood cells (RBC) were sensitised with...
5.
Armour K, Smith C, Turner C, Kirton C, Wilkes A, Hadley A, et al.
Eur J Immunol
. 2013 Nov;
44(3):905-14.
PMID: 24285214
G1Δnab is a mutant human IgG1 constant region with a lower ability to interact with FcγR than the natural IgG constant regions. Radiolabelled RBCs and platelets sensitised with specific G1Δnab...
6.
Kirton C, Gliddon D, Bannish G, Bembridge G, Coney L
Bioanalysis
. 2011 Dec;
3(23):2657-63.
PMID: 22136053
The induction of cytokine release is a common consequence of the administration of therapeutic antibodies and in most cases is either tolerated by the patient or can be managed clinically...
7.
Goodman R, Kirton C, Oostingh G, Schon M, Clark M, Bradley J, et al.
Transplantation
. 2008 Feb;
85(3):471-7.
PMID: 18301339
Background: Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31) plays an important role in leukocyte-endothelial cell adhesion and transmigration. Single nucleotide polymorphisms of PECAM-1 encoding amino acid substitutions at positions 98 leucine/valine...
8.
Kirton C, Laukkanen M, Nieminen A, Merinen M, Stolen C, Armour K, et al.
Eur J Immunol
. 2005 Oct;
35(11):3119-30.
PMID: 16224816
Human vascular adhesion protein-1 (VAP-1) is a homodimeric 170-kDa sialoglycoprotein that is expressed on the surface of endothelial cells and functions as a semicarbazide-sensitive amine oxidase and as an adhesion...