Christopher Jagger
Overview
Explore the profile of Christopher Jagger including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
389
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0
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Recent Articles
1.
Chew C, Brand O, Yamamura T, Lawless C, Morais M, Zeef L, et al.
Matrix Biol
. 2024 Feb;
127:23-37.
PMID: 38331051
Background: The kidney contains distinct glomerular and tubulointerstitial compartments with diverse cell types and extracellular matrix components. The role of immune cells in glomerular environment is crucial for dampening inflammation...
2.
Scott N, Pearmain L, Knight S, Brand O, Morgan D, Jagger C, et al.
Eur Respir J
. 2023 Mar;
61(5).
PMID: 36922030
Background: COVID-19 is associated with a dysregulated immune response but it is unclear how immune dysfunction contributes to the chronic morbidity persisting in many COVID-19 patients during convalescence (long COVID)....
3.
Wilson J, Kealy D, James S, Plowman T, Newling K, Jagger C, et al.
iScience
. 2021 Dec;
25(1):103672.
PMID: 34957382
Inflammatory cytokines and chemokines (CC) drive COVID-19 pathology. Yet, patients with similar circulating CC levels present with different disease severity. Here, we determined 171 microRNAomes from 58 hospitalized COVID-19 patients...
4.
Shuwa H, Shaw T, Knight S, Wemyss K, McClure F, Pearmain L, et al.
Med
. 2021 Apr;
2(6):720-735.e4.
PMID: 33821250
Background: Emerging studies indicate that some coronavirus disease 2019 (COVID-19) patients suffer from persistent symptoms, including breathlessness and chronic fatigue; however, the long-term immune response in these patients presently remains...
5.
Mann E, Menon M, Knight S, Konkel J, Jagger C, Shaw T, et al.
Sci Immunol
. 2020 Sep;
5(51).
PMID: 32943497
COVID-19 pathogenesis is associated with an exaggerated immune response. However, the specific cellular mediators and inflammatory components driving diverse clinical disease outcomes remain poorly understood. We undertook longitudinal immune profiling...
6.
Goenka A, Doherty J, Al-Farsi T, Jagger C, Banka S, Cheesman E, et al.
J Leukoc Biol
. 2020 Sep;
109(6):1147-1154.
PMID: 32930428
The glucose-6-phosphatase catalytic subunit 3 (G6PC3) encodes a ubiquitously expressed enzyme that regulates cytoplasmic glucose availability. Loss-of-function biallelic G6PC3 mutations cause severe congenital neutropenia and a diverse spectrum of extra-hematological...
7.
Morgan D, Casulli J, Chew C, Connolly E, Lui S, Brand O, et al.
Front Immunol
. 2019 Jan;
9:2943.
PMID: 30619303
Secondary infections arise as a consequence of previous or concurrent conditions and occur in the community or in the hospital setting. The events allowing secondary infections to gain a foothold...
8.
Hussell T, Lui S, Jagger C, Morgan D, Brand O
Eur Respir Rev
. 2018 Jun;
27(148).
PMID: 29950305
The pulmonary extracellular matrix (ECM) is a complex network of proteins which primarily defines tissue architecture and regulates various biochemical and biophysical processes. It is a dynamic system comprising two...
9.
Bell T, Brand O, Morgan D, Salek-Ardakani S, Jagger C, Fujimori T, et al.
Matrix Biol
. 2018 Jun;
80:14-28.
PMID: 29933044
Little is known about the impact of viral infections on lung matrix despite its important contribution to mechanical stability and structural support. The composition of matrix also indirectly controls inflammation...
10.
Billinton N, Bruce S, Hansen J, Hastwell P, Jagger C, McComb C, et al.
Mutat Res
. 2010 May;
700(1-2):44-50.
PMID: 20452458
A new protocol has recently been developed and validated for the GreenScreen HC GADD45a-GFP genotoxicity reporter assay, enabling the incorporation of an S9 metabolic activation system into the assay. The...