Christopher J Madden
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Explore the profile of Christopher J Madden including associated specialties, affiliations and a list of published articles.
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82
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3019
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Recent Articles
1.
Santos R, James W, Rehage J, Eggenberger C, Lesser J, Madden C
Oecologia
. 2025 Feb;
207(3):43.
PMID: 40021527
Changes of consumers' trophic niches, the n-dimensional biotic space that allows a species to satisfy its minimum requirements for population growth, are driven in part by shifts in the degree...
2.
Neural circuits of long-term thermoregulatory adaptations to cold temperatures and metabolic demands
Mota C, Madden C
Nat Rev Neurosci
. 2024 Feb;
25(3):143-158.
PMID: 38316956
The mammalian brain controls heat generation and heat loss mechanisms that regulate body temperature and energy metabolism. Thermoeffectors include brown adipose tissue, cutaneous blood flow and skeletal muscle, and metabolic...
3.
Mota C, Madden C
J Therm Biol
. 2023 May;
114:103551.
PMID: 37216765
The mediobasal hypothalamus (MBH) contains heterogeneous neuronal populations that regulate food intake and energy expenditure. However, the role of MBH neurons in the neural control of thermoeffector activity for thermoregulation...
4.
Mota C, Madden C
Neuroscience
. 2023 Apr;
520:84-94.
PMID: 37054945
Oxidation of fat by brown adipose tissue (BAT) contributes to energy balance and heat production. During cold exposure, BAT thermogenesis produces heat to warm the body. Obese subjects and rodents,...
5.
Mota C, Siler D, Burchiel K, Madden C
Neurosci Lett
. 2023 Feb;
799:137130.
PMID: 36792026
Brown adipose tissue (BAT) activity is controlled by the sympathetic nervous system. Activation of BAT has shown significant promise in preclinical studies to elicit weight loss. Since the hypothalamic paraventricular...
6.
Mota C, Madden C
Am J Physiol Regul Integr Comp Physiol
. 2022 Aug;
323(4):R375-R384.
PMID: 35993560
Immune system responses are a vital defense mechanism against pathogens. Inflammatory mediators finely regulate complex inflammatory responses from initiation to resolution. However, in certain conditions, the inflammation is initiated and...
7.
Mota C, Madden C
Brain Behav Immun
. 2022 Apr;
103:109-121.
PMID: 35429606
Infectious diseases and inflammatory conditions recruit the immune system to mount an appropriate acute response that includes the production of cytokines. Cytokines evoke neurally-mediated responses to fight pathogens, such as...
8.
Patrick C, Kominoski J, McDowell W, Branoff B, Lagomasino D, Leon M, et al.
Sci Adv
. 2022 Mar;
8(9):eabl9155.
PMID: 35235355
Tropical cyclones drive coastal ecosystem dynamics, and their frequency, intensity, and spatial distribution are predicted to shift with climate change. Patterns of resistance and resilience were synthesized for 4138 ecosystem...
9.
Conceicao Furber E, Mota C, Veytsman E, Morrison S, Madden C
Am J Physiol Regul Integr Comp Physiol
. 2021 Oct;
321(6):R938-R950.
PMID: 34704845
Systemic administration of dopamine (DA) receptor agonists leads to falls in body temperature. However, the central thermoregulatory pathways modulated by DA have not been fully elucidated. Here we identified a...
10.
Ma J, Pinho M, Harrison C, Chen J, Sun C, Hackett E, et al.
Magn Reson Med
. 2021 Oct;
87(3):1136-1149.
PMID: 34687086
Purpose: This study is to investigate time-resolved C MR spectroscopy (MRS) as an alternative to imaging for assessing pyruvate metabolism using hyperpolarized (HP) [1- C]pyruvate in the human brain. Methods:...