Christopher J Bowman
Overview
Explore the profile of Christopher J Bowman including associated specialties, affiliations and a list of published articles.
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Articles
51
Citations
405
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Recent Articles
1.
Kwak-Kim J, Maier C, Villano C, Bowman C, Brennan F, Stanislaus D, et al.
J Reprod Immunol
. 2025 Feb;
169:104453.
PMID: 39999662
There have been remarkable advancements in understanding the complex and dynamic immune biological processes engaged during all stages of pregnancy. Exquisite control of immune processes is critical to successful outcome...
2.
Zhou J, Bowman C, Markiewicz V, Manickam B, Gomme E, Sellers R, et al.
Vaccines (Basel)
. 2025 Jan;
13(1).
PMID: 39852805
: Respiratory syncytial virus (RSV) infections usually cause mild, cold-like symptoms in most people, but are a leading infectious disease causing infant death and hospitalization and can result in increased...
3.
Catlin N, Cappon G, Davenport S, Stethem C, Nowland W, Campion S, et al.
Reprod Toxicol
. 2024 Aug;
129:108686.
PMID: 39128486
The aim of embryo-fetal developmental toxicity assessments for pharmaceuticals is to inform potential risk of adverse pregnancy outcome, which has traditionally relied on studies in pregnant animals. Recent updates to...
4.
Federspiel J, Catlin N, Nowland W, Stethem C, Mathialagan N, Fernandez Ocana M, et al.
Mol Cell Proteomics
. 2024 Jun;
23(7):100797.
PMID: 38866076
Targeted protein degradation is the selective removal of a protein of interest through hijacking intracellular protein cleanup machinery. This rapidly growing field currently relies heavily on the use of the...
5.
Bowman C, Campion S, Catlin N, Nowland W, Stethem C, Radi Z, et al.
Birth Defects Res
. 2024 May;
116(5):e2345.
PMID: 38716582
Background: Abrocitinib is a Janus kinase (JAK) 1 selective inhibitor approved for the treatment of atopic dermatitis. Female reproductive tissues were unaffected in general toxicity studies, but an initial female...
6.
Campion S, Bowman C, Fuchs A, Karanian D, Rana P, Cappon G
Birth Defects Res
. 2022 Nov;
115(3):348-356.
PMID: 36367445
Achondroplasia is an autosomal disorder caused by point mutation in the gene encoding fibroblast growth factor receptor 3 (FGFR3) and resulting in gain of function. Recifercept is a potential disease...
7.
Catlin N, Bowman C, Campion S, Lewis E, Nowland W, Stethem C, et al.
Toxicol Sci
. 2022 Jul;
189(2):225-236.
PMID: 35866640
Ervogastat (PF-06865571) is a small molecule diacylglycerol acyltransferase 2 (DGAT2) inhibitor being developed for the oral treatment of nonalcoholic steatohepatitis (NASH) with liver fibrosis. DGAT2 is a key enzyme in...
8.
Buetow B, Cappon G, Aschenbrenner L, Updyke L, Torti V, Evans M, et al.
Int J Toxicol
. 2022 Jun;
41(5):389-401.
PMID: 35672934
Bococizumab is an anti-PCSK9 monoclonal antibody that was intended for the treatment of hypercholesterolemia. After reviewing the 6-month rat toxicity study data, in which there was a low spontaneous tumor...
9.
Bowman C, Becourt-Lhote N, Boulifard V, Cordts R, Corriol-Rohou S, Enright B, et al.
Clin Pharmacol Ther
. 2022 Apr;
113(2):226-245.
PMID: 35388453
This review presents a European Federation of Pharmaceutical Industries and Association/PreClinical Development Expert Group (EFPIA-PDEG) topic group consensus on a data-driven approach to harmonized contraception recommendations for clinical trial protocols...
10.
Bowman C, Medeiros F, Fadare O, Sangoi A, Horvai A, Devine W, et al.
Int J Gynecol Pathol
. 2022 Feb;
42(1):1-10.
PMID: 35180768
Gynecologic tract origin of inflammatory myofibroblastic tumor (IMT), a receptor tyrosine kinase fusion driven tumor with malignant potential, is uncommon and mostly involves the uterine corpus where misclassification as a...