Christopher Gregg
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Explore the profile of Christopher Gregg including associated specialties, affiliations and a list of published articles.
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Articles
38
Citations
1938
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Recent Articles
1.
Permuth J, Park M, Chen D, Basinski T, Powers B, Gwede C, et al.
Front Oncol
. 2024 Aug;
14:1362244.
PMID: 39109281
Introduction: Cancer-associated cachexia (CC) is a progressive syndrome characterized by unintentional weight loss, muscle atrophy, fatigue, and poor outcomes that affects most patients with pancreatic ductal adenocarcinoma (PDAC). The ability...
2.
Park M, Whelan C, Ahmed S, Boeringer T, Brown J, Crowder S, et al.
Cancers (Basel)
. 2024 Jul;
16(13).
PMID: 39001427
For many patients, the cancer continuum includes a syndrome known as cancer-associated cachexia (CAC), which encompasses the unintended loss of body weight and muscle mass, and is often associated with...
3.
Ferris E, Gonzalez Murcia J, Cristina Rodriguez A, Steinwand S, Stacher Horndli C, Traenkner D, et al.
bioRxiv
. 2024 Jul;
PMID: 38979381
Elucidating the genetic basis of mammalian metabolism could help define mechanisms central to health and disease. Here, we define conserved regulatory elements (CREs) and programs for mammalian metabolic control. We...
4.
Steinwand S, Stacher Horndli C, Ferris E, Emery J, Gonzalez Murcia J, Cristina Rodriguez A, et al.
bioRxiv
. 2024 Jul;
PMID: 38979203
Our study elucidates functional roles for conserved elements associated with the evolution of mammalian hibernation. Genomic analyses found topologically associated domains (TADs) that disproportionately accumulated convergent genomic changes in hibernators,...
5.
Biass S, Reyes-Hardy M, Gregg C, Di Maio L, Dominguez L, Frischknecht C, et al.
Bull Volcanol
. 2024 Jan;
86(2):10.
PMID: 38205134
Supplementary Information: The online version contains supplementary material available at 10.1007/s00445-023-01700-w.
6.
Ravens A, Stacher-Horndli C, Emery J, Steinwand S, Shepherd J, Gregg C
iScience
. 2023 May;
26(5):106761.
PMID: 37216088
Foraging in animals relies on innate decision-making heuristics that can result in suboptimal cognitive biases in some contexts. The mechanisms underlying these biases are not well understood, but likely involve...
7.
Kravitz S, Ferris E, Love M, Thomas A, Quinlan A, Gregg C
Cell Rep
. 2023 Jan;
42(1):111945.
PMID: 36640362
Genes are typically assumed to express both parental alleles similarly, yet cell lines show random allelic expression (RAE) for many autosomal genes that could shape genetic effects. Thus, understanding RAE...
8.
Bonthuis P, Steinwand S, Stacher Horndli C, Emery J, Huang W, Kravitz S, et al.
Cell Rep
. 2022 Mar;
38(10):110500.
PMID: 35263575
Noncanonical genomic imprinting can cause biased expression of one parental allele in a tissue; however, the functional relevance of such biases is unclear. To investigate ethological roles for noncanonical imprinting...
9.
Tollis M, Ferris E, Campbell M, Harris V, Rupp S, Harrison T, et al.
Mol Biol Evol
. 2021 May;
38(9):3606-3620.
PMID: 33944920
Disease susceptibility and resistance are important factors for the conservation of endangered species, including elephants. We analyzed pathology data from 26 zoos and report that Asian elephants have increased neoplasia...
10.
Ferris E, Gregg C
Cell Rep
. 2019 Nov;
29(9):2608-2620.e4.
PMID: 31775032
Obesity is a clinical problem and an important adaptation in many species. Hibernating mammals, for example, become obese, insulin resistant, and hyperinsulinemic to store fat. Here, we combine comparative phylogenomics...