Christopher Grainge
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Explore the profile of Christopher Grainge including associated specialties, affiliations and a list of published articles.
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53
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1116
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Recent Articles
1.
Li R, Tan D, Tedja C, Cooper W, Jo H, Grainge C, et al.
Respirology
. 2025 Feb;
PMID: 39919729
Background And Objective: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive lung disease with a poor prognosis. Antifibrotics slow the decline of pulmonary function after 12-months, but limited studies have...
2.
Liu L, Zhang J, Wood S, Newell F, Leonard C, Koufariotis L, et al.
BMC Genomics
. 2024 Sep;
25(1):898.
PMID: 39350042
Background: Lung cancer is a heterogeneous disease and the primary cause of cancer-related mortality worldwide. Somatic mutations, including large structural variants, are important biomarkers in lung cancer for selecting targeted...
3.
Li A, Teoh A, Troy L, Glaspole I, Wilsher M, de Boer S, et al.
Thorax
. 2024 Sep;
79(11):1024-1032.
PMID: 39317451
Background: Lung function testing remains a cornerstone in the assessment and management of interstitial lung disease (ILD) patients. The clinical implications of the Global Lung function Initiative (GLI) reference equations...
4.
Varricchi G, Brightling C, Grainge C, Lambrecht B, Chanez P
Eur Respir J
. 2024 Apr;
63(4).
PMID: 38609094
Asthma is a chronic, heterogeneous disease of the airways, often characterised by structural changes known collectively as airway remodelling. In response to environmental insults, including pathogens, allergens and pollutants, the...
5.
Fielding D, Lakis V, Dalley A, Chittoory H, Newell F, Koufariotis L, et al.
Cancers (Basel)
. 2024 Feb;
16(4).
PMID: 38398180
Endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is often the only source of tumor tissue from patients with advanced, inoperable lung cancer. EBUS-TBNA aspirates are used for the diagnosis, staging, and...
6.
Mackintosh J, Keir G, Troy L, Holland A, Grainge C, Chambers D, et al.
Respirology
. 2024 Jan;
29(2):105-135.
PMID: 38211978
Idiopathic pulmonary fibrosis (IPF) is a progressive disease leading to significant morbidity and mortality. In 2017 the Thoracic Society of Australia and New Zealand (TSANZ) and Lung Foundation Australia (LFA)...
7.
Gibson P, Urroz Guerrero P, Poon C, Rutherford N, Brooker B, Smith A, et al.
J Allergy Clin Immunol Pract
. 2023 Dec;
12(4):929-935.e4.
PMID: 38151119
Background: Ventilation heterogeneity (VH) is a feature of asthma and indicates small airway disease. Nuclear imaging methods assess VH, which can facilitate clinical diagnosis and further our understanding of disease...
8.
Ramsahai J, Simpson J, Cook A, Gibson P, McDonald V, Grainge C, et al.
Thorax
. 2023 Mar;
78(9):868-874.
PMID: 36948587
Introduction: Biomarkers are used to select biologic therapies for patients with severe asthma, but not to regularly adjust therapy, especially oral corticosteroids (OCS). Objective: Our goal was to test the...
9.
West A, Chaudhuri N, Barczyk A, Wilsher M, Hopkins P, Glaspole I, et al.
Thorax
. 2023 Mar;
78(9):882-889.
PMID: 36948586
Introduction: Oral pirfenidone reduces lung function decline and mortality in patients with idiopathic pulmonary fibrosis (IPF). Systemic exposure can have significant side effects, including nausea, rash, photosensitivity, weight loss and...
10.
Humphries S, Mackintosh J, Jo H, Walsh S, Silva M, Calandriello L, et al.
Respirology
. 2022 Jul;
27(12):1045-1053.
PMID: 35875881
Background And Objective: Prediction of disease course in patients with progressive pulmonary fibrosis remains challenging. The purpose of this study was to assess the prognostic value of lung fibrosis extent...