Christopher Ede
Overview
Explore the profile of Christopher Ede including associated specialties, affiliations and a list of published articles.
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Articles
9
Citations
150
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0
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Recent Articles
1.
Meyer D, Ceballos S, Gore S, Liu J, Reginato G, Cano-Linares M, et al.
bioRxiv
. 2024 Jun;
PMID: 38915629
Stalled replication forks can be processed by several distinct mechanisms collectively called post-replication repair which includes homologous recombination, fork regression, and translesion DNA synthesis. However, the regulation of the usage...
2.
Jenkins S, Gore S, Guo X, Liu J, Ede C, Veaute X, et al.
Genetics
. 2019 May;
212(4):1133-1145.
PMID: 31142613
Srs2, in addition to its well-documented antirecombination activity, has been proposed to play a role in promoting synthesis-dependent strand annealing (SDSA). Here we report the identification and characterization of an...
3.
Liu J, Ede C, Wright W, Gore S, Jenkins S, Freudenthal B, et al.
Elife
. 2017 May;
6.
PMID: 28535142
Synthesis-dependent strand annealing (SDSA) is the preferred mode of homologous recombination in somatic cells leading to an obligatory non-crossover outcome, thus avoiding the potential for chromosomal rearrangements and loss of...
4.
Ho P, Ede C, Chen Y
ACS Synth Biol
. 2017 May;
6(8):1484-1495.
PMID: 28510446
Targeted therapies promise to increase the safety and efficacy of treatments against diseases ranging from cancer to viral infections. However, the vast majority of targeted therapeutics relies on the recognition...
5.
Ede C, Chen X, Lin M, Chen Y
ACS Synth Biol
. 2016 Feb;
5(5):395-404.
PMID: 26883397
Inducible transcription systems play a crucial role in a wide array of synthetic biology circuits. However, the majority of inducible promoters are constructed from a limited set of tried-and-true promoter...
6.
Ede C, Rudolph C, Lehmann S, Schurer K, Kramer W
DNA Repair (Amst)
. 2010 Oct;
10(1):45-55.
PMID: 20951099
Stalling of replication forks at lesions is a serious threat to genomic integrity and cell viability. Cells have developed a variety of pathways that allow continuation of synthesis, including translesion...
7.
Panico E, Ede C, Schildmann M, Schurer K, Kramer W
Yeast
. 2009 Nov;
27(1):11-27.
PMID: 19918932
In yeast as in human, DNA helicases play critical roles in assisting replication fork progression. The Saccharomyces cerevisiae MPH1 gene, homologue of human FANCM, has been involved in homologous recombination...
8.
Figl M, Ede C, Hummel J, Wanschitz F, Ewers R, Bergmann H, et al.
IEEE Trans Med Imaging
. 2005 Nov;
24(11):1492-9.
PMID: 16279085
Ever since the development of the first applications in image-guided therapy (IGT), the use of head-mounted displays (HMDs) was considered an important extension of existing IGT technologies. Several approaches to...
9.
Wobbled splatting--a fast perspective volume rendering method for simulation of x-ray images from CT
Birkfellner W, Seemann R, Figl M, Hummel J, Ede C, Homolka P, et al.
Phys Med Biol
. 2005 Apr;
50(9):N73-84.
PMID: 15843725
3D/2D registration, the automatic assignment of a global rigid-body transformation matching the coordinate systems of patient and preoperative volume scan using projection images, is an important topic in image-guided therapy...