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Christopher Copeland

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Articles 18
Citations 78
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Recent Articles
1.
Thevkar Nagesh P, Cho Y, Zhuang Y, Babuta M, Ortega-Ribera M, Joshi R, et al.
Sci Transl Med . 2024 Aug; 16(759):eadg1915. PMID: 39110779
Severe alcohol-associated hepatitis (AH) is a life-threatening form of alcohol-associated liver disease. Liver neutrophil infiltration is a hallmark of AH, yet the effects of alcohol on neutrophil functions remain elusive....
2.
Borrell J, Karumattu Manattu A, Copeland C, Fraser K, DOvidio A, Granatowicz Z, et al.
Brain Commun . 2024 Jul; 6(4):fcae044. PMID: 38978721
Paediatrics with congenital upper-limb reduction deficiency often face difficulties with normal development such as motor skills, needing assistance with daily activities such as self-care limitations with certain movements, sports, or...
3.
Babuta M, Morel C, de Carvalho Ribeiro M, Datta A, Calenda C, Copeland C, et al.
Hepatol Commun . 2024 Jun; 8(7). PMID: 38896082
Background: The recent increase in the incidence of alcohol-associated hepatitis (AH) coincides with the obesity epidemic in the United States. However, current mouse models do not fully replicate the combined...
4.
Babuta M, Morel C, de Carvalho Ribeiro M, Calenda C, Ortega-Ribera M, Thevkar Nagesh P, et al.
Gut . 2024 May; 73(11):1854-1869. PMID: 38777573
Objective: Alcohol use in metabolic dysfunction-associated steatohepatitis (MASH) is associated with an increased risk of fibrosis and liver-related death. Here, we aimed to identify a mechanism through which repeated alcohol...
5.
Fraser K, Kuhn M, Swanson R, Coulter D, Copeland C, Zuniga J
Children (Basel) . 2023 Aug; 10(8). PMID: 37628286
The main objective of this study was to describe the cortical patterns of brain activity during a gross dexterity task and develop a behavioral profile of children experiencing isolation. A...
6.
Karumattu Manattu A, Borrell J, Copeland C, Fraser K, Zuniga J
Front Rehabil Sci . 2023 Jun; 4:1156940. PMID: 37266515
Introduction: A short-term immobilization of one hand affects musculoskeletal functions, and the associated brain network adapts to the alterations happening to the body due to injuries. It was hypothesized that...
7.
Borrell J, Karumattu Manattu A, Copeland C, Fraser K, DOvidio A, Granatowicz Z, et al.
Front Neurosci . 2023 May; 17:1130050. PMID: 37234264
Targeted muscle reinnervation (TMR) surgery involves the coaptation of amputated nerves to nearby motor nerve branches with the purpose of reclosing the neuromuscular loop in order to reduce phantom limb...
8.
de Carvalho Ribeiro M, Cho Y, Mehta J, Wang X, Babuta M, Copeland C, et al.
Liver Int . 2023 May; 43(9):1937-1949. PMID: 37222257
Background & Aims: Various intracellular pathways regulate inflammation in NASH. Cyclic GMP-AMP synthase (cGAS) is a DNA sensor that activates STING and plays a role in inflammatory diseases. Here, we...
9.
de Carvalho Ribeiro M, Iracheta-Vellve A, Babuta M, Calenda C, Copeland C, Zhuang Y, et al.
Hepatology . 2023 Mar; 78(1):225-242. PMID: 36862512
Background Aims: Prolonged systemic inflammation contributes to poor clinical outcomes in severe alcohol-associated hepatitis (AH) even after the cessation of alcohol use. However, mechanisms leading to this persistent inflammation remain...
10.
Cho Y, Joshi R, Lowe P, Copeland C, Ribeiro M, Morel C, et al.
Hepatol Commun . 2022 Aug; 6(9):2322-2339. PMID: 35997009
Massive inflammation and liver failure are main contributors to the high mortality in alcohol-associated hepatitis (AH). In recent clinical trials, granulocyte colony-stimulating factor (G-CSF) therapy improved liver function and survival...