Christopher Christophi
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Explore the profile of Christopher Christophi including associated specialties, affiliations and a list of published articles.
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Articles
126
Citations
3201
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Recent Articles
1.
Riddiough G, Fifis T, Muralidharan V, Christophi C, Tran B, Perini M, et al.
Int J Mol Sci
. 2024 Mar;
25(6).
PMID: 38542253
The recurrence of colorectal liver metastasis (CRLM) following liver resection is common; approximately 40% of patients will experience tumor recurrence post-surgery. Renin-angiotensin inhibitors (RASis) have been shown to attenuate the...
2.
Preston S, Stutz M, Allison C, Nachbur U, Gouil Q, Tran B, et al.
Gastroenterology
. 2022 Aug;
163(6):1643-1657.e14.
PMID: 36037995
Background & Aims: Necroptosis is a highly inflammatory mode of cell death that has been implicated in causing hepatic injury including steatohepatitis/ nonalcoholic steatohepatitis (NASH); however, the evidence supporting these...
3.
Walsh K, Kastrappis G, Fifis T, Paolini R, Christophi C, Perini M
Cancers (Basel)
. 2022 Jun;
14(11).
PMID: 35681695
Most patients with colorectal cancer (CRC) develop metastases, predominantly in the liver (CLM). Targeted therapies are being investigated to improve current CLM treatments. This study tested the effectiveness of SAR131675,...
4.
Riddiough G, Walsh K, Fifis T, Kastrappis G, Tran B, Vincan E, et al.
Int J Mol Sci
. 2022 May;
23(9).
PMID: 35563674
(1) Liver regeneration following partial hepatectomy for colorectal liver metastasis (CRLM) has been linked to tumour recurrence. Inhibition of the renin−angiotensin system (RASi) attenuates CRLM growth in the non-regenerating liver....
5.
Walcott J, Fink M, Ealing I, Christophi C, Muralidharan V
ANZ J Surg
. 2021 Nov;
91(12):2669-2674.
PMID: 34723420
Background: Liver transplantation is an established treatment for liver failure, and its success relies on the quality of the donated organ amongst other factors. Studies on procurement-related liver injury (PRLI)...
6.
Yoshino O, Wong B, Cox D, Lee E, Hepworth G, Christophi C, et al.
J Gastroenterol Hepatol
. 2021 Aug;
36(12):3500-3507.
PMID: 34425021
Background And Aim: The role of circulating mitochondrial DNA (cmtDNA) in transplantation remains to be elucidated. cmtDNA may be released into the circulation as a consequence of liver injury; yet...
7.
Louis M, Johnston S, Churilov L, Ma R, Christophi C, Weinberg L
Medicine (Baltimore)
. 2021 Jul;
100(27):e26546.
PMID: 34232193
Background: Colonic resection is a common surgical procedure that is associated with a high rate of postoperative complications. Postoperative complications are expected to be major contributors to hospital costs. Therefore,...
8.
Riddiough G, Fifis T, Walsh K, Muralidharan V, Christophi C, Tran B, et al.
Cancers (Basel)
. 2021 Jun;
13(11).
PMID: 34073112
(1) Background: Recent clinical and experimental data suggests that the liver's regenerative response following partial hepatectomy can stimulate tumor recurrence in the liver remnant. The Wnt/β-catenin pathway plays important roles...
9.
Tang J, Churilov L, Tan C, Hu R, Pearce B, Cosic L, et al.
BMC Anesthesiol
. 2020 Aug;
20(1):207.
PMID: 32814546
Background: Our study aimed to test the hypothesis that the addition of intrathecal morphine (ITM) results in reduced postoperative opioid use and enhanced postoperative analgesia in patients undergoing open liver...
10.
Tran B, Flanagan D, Ebert G, Warner N, Tran H, Fifis T, et al.
Cancers (Basel)
. 2020 Jun;
12(6).
PMID: 32486480
An emerging theme for Wnt-addicted cancers is that the pathway is regulated at multiple steps via various mechanisms. Infection with hepatitis B virus (HBV) is a major risk factor for...