Christopher C Nguyen
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Explore the profile of Christopher C Nguyen including associated specialties, affiliations and a list of published articles.
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10
Citations
306
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Recent Articles
1.
Zhang H, Read C, Nguyen C, Siddiquey M, Shang C, Hall C, et al.
mBio
. 2019 Dec;
10(6).
PMID: 31822584
Human cytomegalovirus (HCMV) encodes an endoplasmic reticulum (ER)-resident glycoprotein, UL148, which activates the unfolded protein response (UPR) but is fully dispensable for viral replication in cultured cells. Hence, its previously...
2.
Nguyen C, Domma A, Zhang H, Kamil J
J Virol
. 2019 Dec;
94(5).
PMID: 31801856
The human cytomegalovirus (HCMV) endoplasmic reticulum (ER)-resident glycoprotein UL148 is posited to play roles in immune evasion and regulation of viral cell tropism. UL148 prevents cell surface presentation of the...
3.
Nguyen C, Kamil J
Viruses
. 2018 Dec;
10(12).
PMID: 30544948
The past few years have brought substantial progress toward understanding how human cytomegalovirus (HCMV) enters the remarkably wide spectrum of cell types and tissues that it infects. Neuropilin-2 and platelet-derived...
4.
Siddiquey M, Zhang H, Nguyen C, Domma A, Kamil J
J Virol
. 2018 Jul;
92(20).
PMID: 30045994
Eukaryotic cells are equipped with three sensors that respond to the accumulation of misfolded proteins within the lumen of the endoplasmic reticulum (ER) by activating the unfolded protein response (UPR),...
5.
Nguyen C, Siddiquey M, Zhang H, Li G, Kamil J
J Virol
. 2018 Jul;
92(18).
PMID: 29997207
UL148 is a viral endoplasmic reticulum (ER)-resident glycoprotein that contributes to human cytomegalovirus (HCMV) cell tropism. The influence of UL148 on tropism correlates with its potential to promote the expression...
6.
Li G, Nguyen C, Ryckman B, Britt W, Kamil J
Proc Natl Acad Sci U S A
. 2015 Apr;
112(14):4471-6.
PMID: 25831500
Viral glycoproteins mediate entry of enveloped viruses into cells and thus play crucial roles in infection. In herpesviruses, a complex of two viral glycoproteins, gH and gL (gH/gL), regulates membrane...
7.
Li G, Rak M, Nguyen C, Umashankar M, Goodrum F, Kamil J
J Virol
. 2014 Mar;
88(11):6047-60.
PMID: 24623439
Unlabelled: We report that UL133-UL138 (UL133/8), a transcriptional unit within the ULb' region (ULb') of the human cytomegalovirus (HCMV) genome, and UL97, a viral protein kinase encoded by HCMV, play...
8.
Wang D, Li G, Schauflinger M, Nguyen C, Hall E, Yurochko A, et al.
J Virol
. 2013 Mar;
87(11):6359-76.
PMID: 23536674
We report a requirement for the viral protein kinase UL97 in human cytomegalovirus (HCMV) replication that maps to the ULb' region of the viral genome. A UL97-null (Δ97) mutant of...
9.
Ke W, Huang S, Hudson L, Elkins K, Nguyen C, Spratt B, et al.
Proc Natl Acad Sci U S A
. 2012 Mar;
109(17):6763-8.
PMID: 22431601
Rates of hospital-acquired infections, specifically methicillin-resistant Staphylococcus aureus (MRSA), are increasingly being used as indicators for quality of hospital hygiene. There has been much effort on understanding the transmission process...
10.
Huang S, Avery T, Song Y, Elkins K, Nguyen C, Nutter S, et al.
Infect Control Hosp Epidemiol
. 2010 Sep;
31(11):1160-9.
PMID: 20874503
Background: Assessments of infectious disease spread in hospitals seldom account for interfacility patient sharing. This is particularly important for pathogens with prolonged incubation periods or carrier states. Methods: We quantified...