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Christoph Alexander Kasper

Explore the profile of Christoph Alexander Kasper including associated specialties, affiliations and a list of published articles. Areas
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Articles 5
Citations 387
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Recent Articles
1.
Milivojevic M, Dangeard A, Kasper C, Tschon T, Emmenlauer M, Pique C, et al.
PLoS Pathog . 2017 Feb; 13(2):e1006224. PMID: 28222186
During infection by invasive bacteria, epithelial cells contribute to innate immunity via the local secretion of inflammatory cytokines. These are directly produced by infected cells or by uninfected bystanders via...
2.
Reiterer V, Grossniklaus L, Tschon T, Kasper C, Sorg I, Arrieumerlou C
Cell Signal . 2011 Mar; 23(7):1188-96. PMID: 21402152
Shigella flexneri type III secreted effector OspF harbors a phosphothreonine lyase activity that irreversibly dephosphorylates MAP kinases (MAPKs) p38 and ERK in infected epithelial cells and thereby, dampens innate immunity....
3.
Kasper C, Sorg I, Schmutz C, Tschon T, Wischnewski H, Kim M, et al.
Immunity . 2010 Nov; 33(5):804-16. PMID: 21093316
The enteroinvasive bacterium Shigella flexneri uses multiple secreted effector proteins to downregulate interleukin-8 (IL-8) expression in infected epithelial cells. Yet, massive IL-8 secretion is observed in Shigellosis. Here we report...
4.
Kim M, Jeong H, Kasper C, Arrieumerlou C
PLoS One . 2010 Oct; 5(10):e15371. PMID: 20976174
Background: During pathogen infection, innate immunity is initiated via the recognition of microbial products by pattern recognition receptors and the subsequent activation of transcription factors that upregulate proinflammatory genes. By...
5.
Boehm A, Kaiser M, Li H, Spangler C, Kasper C, Ackermann M, et al.
Cell . 2010 Mar; 141(1):107-16. PMID: 20303158
Bacteria swim by means of rotating flagella that are powered by ion influx through membrane-spanning motor complexes. Escherichia coli and related species harness a chemosensory and signal transduction machinery that...