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Christof Schaefer

Explore the profile of Christof Schaefer including associated specialties, affiliations and a list of published articles. Areas
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Articles 88
Citations 1031
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Recent Articles
1.
Hoeltzenbein M, Slimi S, Fietz A, Dathe K, Schaefer C
Sci Rep . 2025 Feb; 15(1):5962. PMID: 39966441
No abstract available.
2.
Dathe K, Benndorf C, Bergner S, Schaefer C
Pharmaceuticals (Basel) . 2025 Jan; 17(12. PMID: 39770434
Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used during pregnancy. Due to their fetotoxicity, NSAIDs are contraindicated during the third trimester. There is ongoing controversy about the extent to...
3.
Hoeltzenbein M, Slimi S, Fietz A, Dathe K, Schaefer C
Sci Rep . 2024 Dec; 14(1):30585. PMID: 39715780
Because of their developmental toxicity, some antiseizure medication (ASM) should be avoided during pregnancy. This may lead to discontinuation or switching of ASM after recognition of pregnancy, but some of...
4.
Fietz A, Onken M, Padberg S, Schaefer C, Dathe K
Sci Rep . 2024 Jan; 14(1):674. PMID: 38182639
Effects of valproate (VPA) dose and treatment discontinuation during the first trimester of pregnancy on the risks of spontaneous abortions (SAB) and major birth defects were analyzed. Pregnancies with first...
5.
Onken M, Lohse L, Coulm B, Beghin D, Richardson J, Bermejo-Sanchez E, et al.
Acta Psychiatr Scand . 2023 Dec; 150(5):372-384. PMID: 38110225
Objective: In recent years, safety concerns about modafinil exposure during pregnancy have emerged. In particular, increased risks for major congenital anomalies (MCA) and impaired fetal growth were reported, although study...
6.
Hoeltzenbein M, Bartz I, Fietz A, Lohse L, Onken M, Dathe K, et al.
Epilepsia . 2023 Oct; 65(1):26-36. PMID: 37857460
Objective: Levetiracetam is increasingly used in pregnant women with epilepsy. Although teratogenic effects have not been observed so far, data on the risks of spontaneous abortion and major birth defects...
7.
Hoeltzenbein M, Slimi S, Fietz A, Stegherr R, Onken M, Beyersmann J, et al.
Seizure . 2023 Apr; 107:107-113. PMID: 37003184
Introduction: Epilepsy is a common neurological disease requiring long-term therapy also during pregnancy. Most studies on pregnancy outcomes in women with epilepsy are based on antiseizure medication (ASM) in monotherapy....
8.
Haug U, Kollhorst B, Schink T, Thone K, Dathe K, Schaefer C, et al.
Pharmacoepidemiol Drug Saf . 2022 Nov; 32(2):148-157. PMID: 36401747
Purpose: Large health-care databases are increasingly used for research on drug utilization and safety in pregnancy. For the German Pharmacoepidemiological Research Database (GePaRD), covering ~20% of the German population, algorithms...
9.
Dathe K, Frank J, Padberg S, Hultzsch S, Beck E, Schaefer C
BMC Pregnancy Childbirth . 2022 Aug; 22(1):666. PMID: 36028798
Background: Non-steroidal anti-inflammatory drugs (NSAID) are frequently used to treat pain, fever and inflammatory conditions. Due to evidenced fetotoxicity, treatment with NSAID and metamizole should be avoided in the 3rd...
10.
Stegherr R, Beck E, Hultzsch S, Schaefer C, Dathe K
Reprod Toxicol . 2022 Jun; 111:129-134. PMID: 35644329
Women and their health care provider (HCP) often seek advice for drug safety in pregnancy at Teratology Information Services (TIS). In turn, TIS ask for details of drug exposure and...