Christof Burek
Overview
Explore the profile of Christof Burek including associated specialties, affiliations and a list of published articles.
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10
Citations
493
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Recent Articles
1.
Wilmes A, Limonciel A, Aschauer L, Moenks K, Bielow C, Leonard M, et al.
J Proteomics
. 2012 Dec;
79:180-94.
PMID: 23238060
High content omic techniques in combination with stable human in vitro cell culture systems have the potential to improve on current pre-clinical safety regimes by providing detailed mechanistic information of...
2.
Sauer M, Bretz A, Beinoraviciute-Kellner R, Beitzinger M, Burek C, Rosenwald A, et al.
Nucleic Acids Res
. 2008 Feb;
36(6):1900-12.
PMID: 18267967
The p53 family is known as a family of transcription factors with functions in tumor suppression and development. Whereas the central DNA-binding domain is highly conserved among the three family...
3.
Beitzinger M, Hofmann L, Oswald C, Beinoraviciute-Kellner R, Sauer M, Griesmann H, et al.
EMBO J
. 2008 Feb;
27(5):792-803.
PMID: 18239687
p53 is known to prevent tumour formation by restricting the proliferation of damaged or oncogene-expressing cells. In contrast, how the p53 family member p73 suppresses tumour formation remains elusive. Using...
4.
Brown P, Ashe S, Leich E, Burek C, Barrans S, Fenton J, et al.
Blood
. 2007 Dec;
111(5):2816-24.
PMID: 18077790
The FOXP1 forkhead transcription factor is targeted by recurrent chromosome translocations in several subtypes of B-cell non-Hodgkin lymphomas, where high-level FOXP1 protein expression has been linked to a poor prognosis....
5.
Leich E, Hartmann E, Burek C, Ott G, Rosenwald A
APMIS
. 2007 Nov;
115(10):1135-46.
PMID: 18042147
Gene expression profiling is a powerful tool to uncover complex molecular networks in cancer and, specifically, in malignant lymphomas. Within diffuse large B-cell lymphomas (DLBCL), two major molecular subtypes, the...
6.
Mao Z, Quintanilla-Martinez L, Raffeld M, Richter M, Krugmann J, Burek C, et al.
Am J Surg Pathol
. 2007 Sep;
31(10):1605-14.
PMID: 17895764
Approximately 5% of B-cell chronic lymphocytic leukemia (B-CLL) patients develop a secondary aggressive lymphoma, usually of diffuse large B-cell type (DLBCL), termed Richter's transformation (RT). Rarely, classic Hodgkin lymphoma (HL)...
7.
Nagel S, Burek C, Venturini L, Scherr M, Quentmeier H, Meyer C, et al.
Blood
. 2006 Dec;
109(7):3015-23.
PMID: 17148583
Many members of the nearly 200-strong homeobox gene family have been implicated in cancer, mostly following ectopic expression. In this study we analyzed homeobox gene expression in Hodgkin lymphoma (HL)...
8.
Cam H, Griesmann H, Beitzinger M, Hofmann L, Beinoraviciute-Kellner R, Sauer M, et al.
Cancer Cell
. 2006 Oct;
10(4):281-93.
PMID: 17045206
The p53 family comprises the tumor suppressor p53 and the structural homologs p63 and p73. How the three family members cooperate in tumor suppression remains unclear. Here, we report different...
9.
Bea S, Zettl A, Wright G, Salaverria I, Jehn P, Moreno V, et al.
Blood
. 2005 Jul;
106(9):3183-90.
PMID: 16046532
Gene-expression profiling has identified 3 major subgroups of diffuse large B-cell lymphoma (DLBCL): germinal center B-cell-like (GCB), activated B-cell-like (ABC), and primary mediastinal DLBCL (PMBCL). Using comparative genomic hybridization (CGH),...
10.
Strobel P, Rosenwald A, Beyersdorf N, Kerkau T, Elert O, Murumagi A, et al.
Ann Neurol
. 2004 Nov;
56(6):901-4.
PMID: 15562414
Myasthenia gravis (MG) is the prime autoimmune manifestation of thymomas. We investigated the generation of T cells with a regulatory phenotype (T(R)) in thymomas with and without associated MG. In...