Christo P Christov
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Explore the profile of Christo P Christov including associated specialties, affiliations and a list of published articles.
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11
Citations
363
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Recent Articles
1.
Christov C, Dingwell K, Skehel M, Wilkes H, Sale J, Smith J, et al.
Cell Rep
. 2018 Mar;
22(9):2265-2278.
PMID: 29490265
DNA replication in the embryo of Xenopus laevis changes dramatically at the mid-blastula transition (MBT), with Y RNA-independent random initiation switching to Y RNA-dependent initiation at specific origins. Here, we...
2.
Nagy A, Vazquez-Manrique R, Lopez M, Christov C, Sequedo M, Herzog M, et al.
EMBO Rep
. 2015 Jan;
16(3):341-50.
PMID: 25608529
RNA interference (RNAi) is a widespread and widely exploited phenomenon. Here, we show that changing inositol 1,4,5-trisphosphate (IP3) signalling alters RNAi sensitivity in Caenorhabditis elegans. Reducing IP3 signalling enhances sensitivity...
3.
Martorell O, Merlos-Suarez A, Campbell K, Barriga F, Christov C, Miguel-Aliaga I, et al.
PLoS One
. 2014 Feb;
9(2):e88413.
PMID: 24516653
Whereas the series of genetic events leading to colorectal cancer (CRC) have been well established, the precise functions that these alterations play in tumor progression and how they disrupt intestinal...
4.
Linneweber G, Jacobson J, Busch K, Hudry B, Christov C, Dormann D, et al.
Cell
. 2014 Jan;
156(1-2):69-83.
PMID: 24439370
During adaptive angiogenesis, a key process in the etiology and treatment of cancer and obesity, the vasculature changes to meet the metabolic needs of its target tissues. Although the cues...
5.
Talsma A, Christov C, Terriente-Felix A, Linneweber G, Perea D, Wayland M, et al.
Proc Natl Acad Sci U S A
. 2012 Jul;
109(30):12177-82.
PMID: 22778427
The role of the central neuropeptide pigment-dispersing factor (PDF) in circadian timekeeping in Drosophila is remarkably similar to that of vasoactive intestinal peptide (VIP) in mammals. Like VIP, PDF is...
6.
Collart C, Christov C, Smith J, Krude T
Mol Cell Biol
. 2011 Jul;
31(18):3857-70.
PMID: 21791613
Noncoding Y RNAs are essential for the initiation of chromosomal DNA replication in mammalian cell extracts, but their role in this process during early vertebrate development is unknown. Here, we...
7.
Zhang A, Langley A, Christov C, Kheir E, Shafee T, Gardiner T, et al.
J Cell Sci
. 2011 May;
124(Pt 12):2058-69.
PMID: 21610089
Non-coding Y RNAs are required for the initiation of chromosomal DNA replication in mammalian cells. It is unknown how they perform this function or if they associate with a nuclear...
8.
Langley A, Chambers H, Christov C, Krude T
PLoS One
. 2010 Nov;
5(10):e13673.
PMID: 21060685
Background: Ro ribonucleoprotein particles (Ro RNPs) consist of a non-coding Y RNA bound by Ro60, La and possibly other proteins. The physiological function of Ro RNPs is controversial as divergent...
9.
Krude T, Christov C, Hyrien O, Marheineke K
J Cell Sci
. 2009 Aug;
122(Pt 16):2836-45.
PMID: 19657016
Non-coding Y RNAs have recently been identified as essential novel factors for chromosomal DNA replication in mammalian cell nuclei, but mechanistic details of their function have not been defined. Here,...
10.
Gardiner T, Christov C, Langley A, Krude T
RNA
. 2009 May;
15(7):1375-85.
PMID: 19474146
Noncoding Y RNAs are required for the reconstitution of chromosomal DNA replication in late G1 phase template nuclei in a human cell-free system. Y RNA genes are present in all...