Christine Roman
Overview
Explore the profile of Christine Roman including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
166
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Recent Articles
1.
Waleh N, Seidner S, McCurnin D, Giavedoni L, Hodara V, Goelz S, et al.
Pediatr Res
. 2011 Jun;
70(4):332-8.
PMID: 21691249
Permanent closure of the newborn ductus arteriosus requires the development of neointimal mounds to completely occlude its lumen. VEGF is required for neointimal mound formation. The size of the neointimal...
2.
Kribs-Zaleta C, Lee M, Roman C, Wiley S, Hernandez-Suarez C
Math Biosci Eng
. 2010 Apr;
2(4):771-88.
PMID: 20369952
The AIDS epidemic is having a growing impact on the transport sector of the economy of sub-Saharan Africa, where long-distance truck drivers are at an increased risk of infection due...
3.
Reese J, Waleh N, Poole S, Brown N, Roman C, Clyman R
Pediatr Res
. 2009 Apr;
66(2):155-61.
PMID: 19390487
Although prostaglandin E2 (PGE2) vasodilates the ductus arteriosus, tocolysis with cyclooxygenase (COX) inhibitors delays postnatal ductus arteriosus closure. We used fetal mice and sheep to determine whether PGE2 has a...
4.
Waleh N, Reese J, Kajino H, Roman C, Seidner S, McCurnin D, et al.
Pediatr Res
. 2008 Dec;
65(3):285-90.
PMID: 19092721
Compared with the full-term ductus arteriosus, the premature ductus is less likely to constrict when exposed to postnatal oxygen concentrations. We used isolated fetal sheep ductus arteriosus (pretreated with inhibitors...
5.
Clyman R, Waleh N, Kajino H, Roman C, Mauray F
Am J Physiol Regul Integr Comp Physiol
. 2007 Jul;
293(4):R1650-6.
PMID: 17652360
Studies performed in sheep and baboons have shown that after birth, the normoxic muscle media of ductus arteriosus (DA) becomes profoundly hypoxic as it constricts and undergoes anatomic remodeling. We...
6.
Clyman R, Roman C
Pediatr Res
. 2007 Jun;
62(2):167-9.
PMID: 17597645
Caffeine and other methyl xanthines are widely used in the neonatal period. A recent, randomized, placebo-controlled, multicenter trial found that infants who were randomly assigned to caffeine treatment had less...
7.
Reese J, Anderson J, Brown N, Roman C, Clyman R
Am J Physiol Regul Integr Comp Physiol
. 2006 Jul;
291(6):R1717-1723.
PMID: 16857891
Use of cyclooxygenase (COX) inhibitors to delay preterm birth is complicated by in utero constriction of the ductus arteriosus and delayed postnatal closure. Delayed postnatal closure has been attributed to...
8.
Levin M, McCurnin D, Seidner S, Yoder B, Waleh N, Goldbarg S, et al.
Am J Physiol Regul Integr Comp Physiol
. 2005 Oct;
290(2):R359-64.
PMID: 16223843
After birth, constriction of the full-term ductus arteriosus induces oxygen, glucose and ATP depletion, cell death, and anatomic remodeling of the ductus wall. The immature ductus frequently fails to develop...
9.
Levin M, Goldbarg S, Lindqvist A, Sward K, Roman C, Liu B, et al.
Pediatr Res
. 2005 Mar;
57(6):801-5.
PMID: 15774827
Postnatal constriction of the full-term ductus arteriosus produces cell death and remodeling of the ductus wall. Using a bioluminescence imaging technique, we found that after birth, the lamb ductus develops...
10.
Waleh N, Seidner S, McCurnin D, Yoder B, Liu B, Roman C, et al.
Pediatr Res
. 2004 Dec;
57(2):254-62.
PMID: 15611359
Inflammatory processes play a crucial role in the pathogenesis of atherosclerosis and other vascular disorders. We hypothesized that ischemia of the ductus arteriosus might initiate an active inflammatory response that...