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Christine Porzelius

Explore the profile of Christine Porzelius including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 161
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Recent Articles
1.
Grimm A, Teschner U, Porzelius C, Ludewig K, Zielske J, Witte O, et al.
Crit Care . 2014 Feb; 17(5):R227. PMID: 24499688
Introduction: Muscle ultrasound is emerging as a promising tool in the diagnosis of neuromuscular diseases. The current observational study evaluates the usefulness of muscle ultrasound in patients with severe sepsis...
2.
Axer H, Grimm A, Porzelius C, Teschner U, Schumacher U, Witte O, et al.
BMC Neurol . 2013 Nov; 13:159. PMID: 24176121
Background: Axonal damage in large myelinated nerve fibres occurs in about 70% of patients with severe sepsis, known as critical illness polyneuropathy and contributes significantly to an increased short- and...
3.
Rieg S, Jonas D, Kaasch A, Porzelius C, Peyerl-Hoffmann G, Theilacker C, et al.
PLoS One . 2013 Aug; 8(8):e71259. PMID: 23967176
The clinical course of Staphylococcus aureus bacteremia varies extensively. We sought to determine the relationship between genetic characteristics of the infecting pathogen and clinical outcomes in an exploratory study. In...
4.
Kollert F, Tippelt A, Muller C, Jorres R, Porzelius C, Pfeifer M, et al.
Respir Care . 2012 Dec; 58(7):1204-12. PMID: 23232736
Background: In patients with COPD, chronic anemia is known as an unfavorable prognostic factor. Whether the association between hemoglobin (Hb) levels and long-term survival is restricted to anemia or extends...
5.
Iblher N, Manegold S, Porzelius C, Stark G
Plast Reconstr Surg . 2012 Nov; 130(6):830e-840e. PMID: 23190834
Background: Although a multitude of proposed forehead rejuvenation procedures have been described, long-term and systematic morphometric evaluation is rare. There are no studies comparing endoscopic forehead lifts and transpalpebral browpexy...
6.
Gade S, Porzelius C, Falth M, Brase J, Wuttig D, Kuner R, et al.
BMC Bioinformatics . 2011 Dec; 12:488. PMID: 22188670
Background: One of the main goals in cancer studies including high-throughput microRNA (miRNA) and mRNA data is to find and assess prognostic signatures capable of predicting clinical outcome. Both mRNA...
7.
Porzelius C, Johannes M, Binder H, Beissbarth T
Biom J . 2011 Feb; 53(2):190-201. PMID: 21328603
Classification of patients based on molecular markers, for example into different risk groups, is a modern field in medical research. The aim of this classification is often a better diagnosis...
8.
Binder H, Porzelius C, Schumacher M
Biom J . 2011 Feb; 53(2):170-89. PMID: 21328602
Analysis of molecular data promises identification of biomarkers for improving prognostic models, thus potentially enabling better patient management. For identifying such biomarkers, risk prediction models can be employed that link...
9.
Porzelius C, Schumacher M, Binder H
Stat Med . 2010 Mar; 29(7-8):830-8. PMID: 20213716
When fitting predictive survival models to high-dimensional data, an adequate criterion for selecting model complexity is needed to avoid overfitting. The complexity parameter is typically selected by the predictive partial...
10.
Porzelius C, Binder H, Schumacher M
Bioinformatics . 2009 Jan; 25(6):827-9. PMID: 19176556
Unlabelled: There is a multitude of new techniques that promise to extract predictive information in bioinformatics applications. It has been recognized that a first step for validation of the resulting...