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Christine Mackerness

Explore the profile of Christine Mackerness including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Peters M, Woolfall K, Khan I, Deja E, Mouncey P, Wulff J, et al.
Crit Care . 2019 Mar; 23(1):69. PMID: 30845977
Background: Fever improves pathogen control at a significant metabolic cost. No randomized clinical trials (RCT) have compared fever treatment thresholds in critically ill children. We performed a pilot RCT to...
2.
Peters M, Khan I, Woolfall K, Deja E, Mouncey P, Wulff J, et al.
Health Technol Assess . 2019 Feb; 23(5):1-148. PMID: 30793698
Background: Fever accelerates host immune system control of pathogens but at a high metabolic cost. The optimal approach to fever management and the optimal temperature thresholds used for treatment in...
3.
Peters M, Agbeko R, Davis P, Klein N, Zenasni Z, Jones A, et al.
Pediatr Crit Care Med . 2018 Aug; 19(10):939-948. PMID: 30095746
Objectives: Previous trials in adults with impaired immunity and respiratory failure suggest that early noninvasive ventilation avoids endotracheal intubation and improves survival. No randomized clinical trials have addressed this question...