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Christine Levacher

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Citations 284
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Recent Articles
1.
Habert R, Muczynski V, Grisin T, Moison D, Messiaen S, Frydman R, et al.
Reproduction . 2014 Feb; 147(4):R119-29. PMID: 24497529
Fetal testis is a major target of endocrine disruptors (EDs). During the last 20 years, we have developed an organotypic culture system that maintains the function of the different fetal...
2.
Lehraiki A, Chamaillard C, Krust A, Habert R, Levacher C
Toxicol In Vitro . 2011 Jun; 25(8):1542-7. PMID: 21624456
The widespread consumption of soy-based products raises the issue of the reproductive toxicity of phytoestrogens. Indeed, it is well known that genistein, an isoflavone found in soybeans and soy products,...
3.
Lehraiki A, Messiaen S, Berges R, Canivenc-Lavier M, Auger J, Habert R, et al.
Reprod Toxicol . 2010 Dec; 31(4):424-30. PMID: 21172421
Continuous, low-dose exposure to a phytoestrogen (1 mg/kg/day genistein) and/or to an antiandrogenic food contaminant (1 mg/kg/day vinclozolin) has been recently reported to affect male reproductive tract and fertility [1]...
4.
Habert R, Muczynski V, Lehraiki A, Lambrot R, Lecureuil C, Levacher C, et al.
Folia Histochem Cytobiol . 2010 Jan; 47(5):S67-74. PMID: 20067897
There are great concerns about the increasing incidence of abnormalities in male reproductive function. Human sperm counts have markedly dropped and the rate of testicular cancer has clearly augmented over...
5.
Lehraiki A, Racine C, Krust A, Habert R, Levacher C
Toxicol Sci . 2009 Jul; 111(2):372-82. PMID: 19592451
Data from experiments conducted almost exclusively in the rat have established that some phthalates have deleterious effects on the fetal testis probably due to their antiandrogenic and/or estrogenic effects, but...
6.
Delbes G, Duquenne C, Szenker J, Taccoen J, Habert R, Levacher C
Toxicol Sci . 2007 Jun; 99(1):234-43. PMID: 17569695
There is now compelling evidence that inappropriate exposure to estrogen during fetal or neonatal life could affect adult reproductive functions because the testis is sensitive to estrogens during specific periods...
7.
Delbes G, Levacher C, Habert R
Reproduction . 2006 Sep; 132(4):527-38. PMID: 17008464
In recent years, evidences have accumulated that exposure to environmental components with estrogenic activity causes reproductive disorders in human populations. Studies conducted over the past 50 years have clearly shown...
8.
Delbes G, Levacher C, Duquenne C, Habert R
Med Sci (Paris) . 2005 Dec; 21(12):1083-8. PMID: 16324650
Estrogens are classically known to play a major role in female reproduction, but there is now compelling evidence that they may also be involved in the regulation of male reproductive...
9.
Delbes G, Levacher C, Duquenne C, Racine C, Pakarinen P, Habert R
Endocrinology . 2005 Jan; 146(5):2454-61. PMID: 15661855
It is now accepted that estrogens play a role in male fertility and that exposure to exogenous estrogens during fetal/neonatal life can lead to reproductive disorders in the male. However,...
10.
Delbes G, Levacher C, Pairault C, Racine C, Duquenne C, Krust A, et al.
Endocrinology . 2004 Mar; 145(7):3395-403. PMID: 15044378
Epidemiological, clinical, and experimental studies have suggested that excessive exposure to estrogens during fetal/neonatal life can lead to reproductive disorders and sperm abnormalities in adulthood. However, it is unknown whether...