Christine L Weisshaar
Overview
Explore the profile of Christine L Weisshaar including associated specialties, affiliations and a list of published articles.
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24
Citations
313
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Recent Articles
1.
Kartha S, Weisshaar C, Pietrofesa R, Christofidou-Solomidou M, Winkelstein B
Antioxidants (Basel)
. 2020 Dec;
9(12).
PMID: 33266301
Painful cervical radiculopathy is characterized by chronic neuroinflammation that lowers endogenous antioxidant responses leading to the development of oxidative stress and pain after neural trauma. Therefore, antioxidants such as secoisolariciresinol...
2.
Kent A, Weisshaar C, Venkatesan L, Winkelstein B
Ann Biomed Eng
. 2019 Aug;
48(1):112-120.
PMID: 31385104
Although burst and high-frequency (HF) spinal cord stimulation (SCS) relieve neuropathic pain, their effects on neuronal hyperexcitability have not been compared. Specifically, it is unknown how the recharge components of...
3.
Kartha S, Weisshaar C, Philips B, Winkelstein B
Neuroscience
. 2018 Aug;
388:393-404.
PMID: 30086368
Painful neuropathic injuries are accompanied by robust inflammatory and oxidative stress responses that contribute to the development and maintenance of pain. After neural trauma the inflammatory enzyme cyclooxygenase-2 (COX-2) increases...
4.
Weisshaar C, Kras J, Pall P, Kartha S, Winkelstein B
Neurosci Lett
. 2017 Jul;
655:82-89.
PMID: 28689926
The facet joint is a common source of neck pain, particularly after excessive stretch of its capsular ligament. Peptidergic afferents have been shown to have an important role in the...
5.
Kartha S, Yan L, Weisshaar C, Ita M, Shuvaev V, Muzykantov V, et al.
Adv Healthc Mater
. 2017 Jul;
6(17).
PMID: 28671302
A highly efficient antioxidant is developed by encapsulating superoxide dismutase (SOD) within the aqueous interior of porous polymersomes. The porous polymersomes provide a permeable membrane that allows free superoxide radicals...
6.
Philips B, Weisshaar C, Winkelstein B
Comp Med
. 2017 Feb;
67(1):34-42.
PMID: 28222837
Although neck and low-back pain are common sources of neuropathic pain with high societal costs, the pathophysiology of neuropathic pain is not well-defined. Traditionally, most rodent pain studies rely on...
7.
Barr G, Wang S, Weisshaar C, Winkelstein B
Front Neurol
. 2016 Dec;
7:223.
PMID: 28018284
Neuropathic pain is chronic pain that develops after nerve injury and is less frequent in infants and children than in adults. Likewise, in animal models of neuropathic pain, allodynia and...
8.
Smith J, Galie P, Slochower D, Weisshaar C, Janmey P, Winkelstein B
Biomaterials
. 2015 Dec;
80:96-105.
PMID: 26708087
Many neurological disorders are initiated by blood-brain barrier breakdown, which potentiates spinal neuroinflammation and neurodegeneration. Peripheral neuropathic injuries are known to disrupt the blood-spinal cord barrier (BSCB) and to potentiate...
9.
Kras J, Weisshaar C, Pall P, Winkelstein B
Neurosci Lett
. 2015 Aug;
604:193-8.
PMID: 26240991
Non-physiological stretch of the cervical facet joint's capsular ligament induces persistent behavioral hypersensitivity and spinal neuronal hyperexcitability via an intra-articular NGF-dependent mechanism. Although that ligament is innervated by nociceptors, it...
10.
Crosby N, Weisshaar C, Smith J, Zeeman M, Goodman-Keiser M, Winkelstein B
IEEE Trans Biomed Eng
. 2015 Feb;
62(6):1604-13.
PMID: 25667344
Objective: Spinal cord stimulation (SCS) is widely used to treat neuropathic pain. Burst SCS, an alternative mode of stimulation, reduces neuropathic pain without paresthesia. However, the effects and mechanisms of...