Christine L Childers
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Explore the profile of Christine L Childers including associated specialties, affiliations and a list of published articles.
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Articles
10
Citations
41
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Recent Articles
1.
Hadj-Moussa H, Wade S, Childers C, Storey K
Proteins
. 2020 Dec;
89(5):544-557.
PMID: 33368595
The African clawed frog (Xenopus laevis) withstands prolonged periods of extreme whole-body dehydration that lead to impaired blood flow, global hypoxia, and ischemic stress. During dehydration, these frogs shift from...
2.
Al-Attar R, Childers C, Nguyen V, Pamenter M, Storey K
Comp Biochem Physiol A Mol Integr Physiol
. 2020 Jan;
242:110653.
PMID: 31926299
Naked mole rats (NMRs, Heterocephalus glaber) are among the most hypoxia-tolerant mammals known. They can reduce their metabolic rate (>85%) under severe hypoxia, remain moderately active and recover with no...
3.
Childers C, Tessier S, Storey K
PeerJ
. 2019 Sep;
7:e7587.
PMID: 31534849
Background: Thirteen-lined ground squirrels ( experience dramatic changes in physiological and molecular parameters during winter hibernation. Notably, these animals experience reduced blood circulation during torpor, which can put numerous stresses...
4.
Le Tri D, Childers C, Adam M, Ben R, Storey K, Biggar K
J Therm Biol
. 2019 Aug;
84:426-430.
PMID: 31466782
Fr10 is a secreted freeze-responsive protein found in the wood frog (Rana sylvatica). This protein has gained notable research attention for its highly dynamic expression in response to seasonal freezing...
5.
Childers C, Storey K
J Comp Physiol B
. 2019 Jan;
189(2):271-281.
PMID: 30631901
The African clawed frog, Xenopus laevis endures whole body dehydration which can increase its reliance on anaerobic glycolysis for energy production. This makes the regulation of the terminal enzyme of...
6.
Mattice A, MacLean I, Childers C, Storey K
PeerJ
. 2018 Jun;
6:e4918.
PMID: 29900073
Background: Pyruvate kinase (PK) is responsible for the final reaction in glycolysis. As PK is a glycolytic control point, the analysis of PK posttranslational modifications (PTM) and kinetic changes reveals...
7.
Luu B, Green S, Childers C, Holahan M, Storey K
Neurotoxicology
. 2017 Feb;
59:98-104.
PMID: 28192093
Previous studies have shown that di(2-ethylhexyl) phthalate (DEHP) exposure impairs the normal development of pre- and post-synaptic elements of the male, but not female, rat hippocampus. While males seem to...
8.
Ruberto A, Childers C, Storey K
Comp Biochem Physiol B Biochem Mol Biol
. 2016 Aug;
202:48-55.
PMID: 27521690
Cytosolic glycerol-3-phosphate dehydrogenase (G3PDH, EC 1.1.1.8) is an important branch point enzyme connecting lipid metabolism and carbohydrate metabolism. We investigated the dynamic nature of G3PDH by purifying the enzyme from...
9.
Childers C, Green S, Dawson N, Storey K
Anal Biochem
. 2016 Jun;
508:114-7.
PMID: 27296634
The effect of protein stability on kinetic function is monitored with many techniques that often require large amounts of expensive substrates and specialized equipment not universally available. We present differential...
10.
Childers C, Storey K
Protein J
. 2016 Jan;
35(1):61-71.
PMID: 26797504
Xenopus laevis endure substantial dehydration which can impose hypoxic stress due to impaired blood flow. Tissues may increase reliance on anaerobic glycolysis for energy production making the regulation of hexokinase...