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Christina Vianden

Explore the profile of Christina Vianden including associated specialties, affiliations and a list of published articles. Areas
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Articles 3
Citations 180
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Recent Articles
1.
Sharma M, Khong H, Faak F, Bentebibel S, Janssen L, Chesson B, et al.
Nat Commun . 2020 Feb; 11(1):661. PMID: 32005826
High dose interleukin-2 (IL-2) is active against metastatic melanoma and renal cell carcinoma, but treatment-associated toxicity and expansion of suppressive regulatory T cells (Tregs) limit its use in patients with...
2.
Hailemichael Y, Woods A, Fu T, He Q, Nielsen M, Hasan F, et al.
J Clin Invest . 2018 Feb; 128(4):1338-1354. PMID: 29480817
Anticancer vaccination is a promising approach to increase the efficacy of cytotoxic T lymphocyte-associated protein 4 (CTLA-4) and programmed death ligand 1 (PD-L1) checkpoint blockade therapies. However, the landmark FDA...
3.
Singh M, Vianden C, Cantwell M, Dai Z, Xiao Z, Sharma M, et al.
Nat Commun . 2017 Nov; 8(1):1447. PMID: 29129918
CD40 agonists bind the CD40 molecule on antigen-presenting cells and activate them to prime tumor-specific CD8 T cell responses. Here, we study the antitumor activity and mechanism of action of...