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Christina Grimm

Explore the profile of Christina Grimm including associated specialties, affiliations and a list of published articles. Areas
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Articles 40
Citations 1196
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Recent Articles
1.
Kapanaiah S, Grimm C, Katzel D
Schizophrenia (Heidelb) . 2024 Oct; 10(1):90. PMID: 39379378
Hyperactivity of the human anterior hippocampus has been reported to spread from its CA1 subfield to the subiculum around the onset of first-episode psychosis and could be a cellular target...
2.
Grimm C, Duss S, Privitera M, Munn B, Karalis N, Frassle S, et al.
Nat Neurosci . 2024 Sep; 27(11):2167-2177. PMID: 39284964
Noradrenaline (NA) release from the locus coeruleus (LC) changes activity and connectivity in neuronal networks across the brain, modulating multiple behavioral states. NA release is mediated by both tonic and...
3.
Pacholewska A, Lienhard M, Bruggemann M, Hanel H, Bilalli L, Konigs A, et al.
Genome Res . 2024 Sep; 34(11):1832-1848. PMID: 39271291
Mutations in splicing factor 3B subunit 1 () frequently occur in patients with chronic lymphocytic leukemia (CLL) and myelodysplastic syndromes (MDSs). These mutations have different effects on the disease prognosis...
4.
Grimm C, Wenderoth N, Zerbi V
STAR Protoc . 2022 Oct; 3(4):101761. PMID: 36240060
Functional magnetic resonance imaging (fMRI) in mouse brain, paired with spatially and temporally defined manipulations, offers a powerful tool to causally explain the effect of specific neuronal activity on brain...
5.
Grimm C, Herling C, Komnidi A, Hussong M, Kreuzer K, Hallek M, et al.
Biomark Insights . 2022 Jan; 17:11772719211067972. PMID: 35095271
Background: Methylation at 5 CpG sites was previously shown to classify chronic lymphocytic leukemia (CLL) into 3 prognostic subgroups. Here, we aimed to validate the marker set in an additional...
6.
Grimm C, Frassle S, Steger C, von Ziegler L, Sturman O, Shemesh N, et al.
Cell Rep . 2021 Dec; 37(13):110161. PMID: 34965430
The basal ganglia (BG) are a group of subcortical nuclei responsible for motor and executive function. Central to BG function are striatal cells expressing D1 (D1R) and D2 (D2R) dopamine...
7.
Perne C, Peters S, Cartolano M, Horpaopan S, Grimm C, Altmuller J, et al.
PLoS One . 2021 Nov; 16(11):e0259185. PMID: 34843512
The spectrum of somatic genetic variation in colorectal adenomas caused by biallelic pathogenic germline variants in the MSH3 gene, was comprehensively analysed to characterise mutational signatures and identify potential driver...
8.
Mirabella F, Desiato G, Mancinelli S, Fossati G, Rasile M, Morini R, et al.
Immunity . 2021 Nov; 54(11):2611-2631.e8. PMID: 34758338
Early prenatal inflammatory conditions are thought to be a risk factor for different neurodevelopmental disorders. Maternal interleukin-6 (IL-6) elevation during pregnancy causes abnormal behavior in offspring, but whether these defects...
9.
Pacholewska A, Grimm C, Herling C, Lienhard M, Konigs A, Timmermann B, et al.
Int J Mol Sci . 2021 Sep; 22(17). PMID: 34502260
Mutations in splicing factor genes have a severe impact on the survival of cancer patients. Splicing factor 3b subunit 1 () is one of the most frequently mutated genes in...
10.
Markicevic M, Savvateev I, Grimm C, Zerbi V
Transl Psychiatry . 2021 Sep; 11(1):457. PMID: 34482367
In the past decade, the idea that single populations of neurons support cognition and behavior has gradually given way to the realization that connectivity matters and that complex behavior results...