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Christiane Schumann

Explore the profile of Christiane Schumann including associated specialties, affiliations and a list of published articles. Areas
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Articles 10
Citations 271
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Recent Articles
1.
Riabov V, Mossner M, Stohr A, Jann J, Streuer A, Schmitt N, et al.
Br J Haematol . 2021 Jan; 192(5):879-891. PMID: 33486765
Ineffective erythropoiesis and iron overload are common in myelodysplastic syndromes (MDS). Erythroferrone (ERFE) and growth/differentiation factor 15 (GDF15) are two regulators of iron homeostasis produced by erythroid progenitors. Elevated systemic...
2.
Nolte F, Nuckel H, Schmidt B, Geer T, Rubanov O, Hebart H, et al.
J Cancer Res Clin Oncol . 2018 May; 144(8):1531-1538. PMID: 29761371
Background: Iron overload (IOL) due to repetitive transfusions of packed red blood cells (pRBC) has a major impact on morbidity and mortality in patients with inherited bone marrow failure syndromes...
3.
Boch T, Luft T, Metzgeroth G, Mossner M, Jann J, Nowak D, et al.
Leuk Res . 2018 Mar; 68:62-69. PMID: 29549809
In low risk MDS, increased apoptosis of erythroid progenitors mediated via CD95 (Fas) activation has been described to result in peripheral cytopenia. Blockade of the CD95 system can improve erythropoiesis...
4.
Nolte F, Giehl M, Haass W, Nowak V, Schumann C, Nowak D, et al.
Ann Hematol . 2013 May; 92(10):1325-33. PMID: 23645217
Centrosomes play important roles in the maintenance of genetic stability and centrosomal aberrations are a hallmark of cancer. Deregulation of centriole duplication leads to supernumerary centrosomes, sister chromatid missegregation and...
5.
Nolte F, Schumann C, Klein S, Reinwald M, Hofmann W
J Cancer Res Clin Oncol . 2012 Feb; 138(6):953-7. PMID: 22358300
Background: Myelodysplastic syndromes (MDS) are mainly a disease of the elderly. Commonly, MDS patients are treated in an outpatient setting making hematological/oncological private practices (PP) an important backbone in the...
6.
Nolte F, Angelucci E, Beris P, Macwhannell A, Selleslag D, Schumann C, et al.
Leuk Res . 2011 Jul; 35(9):1131-5. PMID: 21737138
Myelodysplastic syndromes are characterized by ineffective hematopoiesis resulting in peripheral cytopenias. The majority of patients is dependent on regular transfusions of packed red blood cells leading to a secondary iron...
7.
Thol F, Friesen I, Damm F, Yun H, Weissinger E, Krauter J, et al.
J Clin Oncol . 2011 May; 29(18):2499-506. PMID: 21576631
Purpose: To study the incidence and prognostic impact of mutations in Additional sex comb-like 1 (ASXL1) in a large cohort of patients with myelodysplastic syndrome (MDS). Patients, Materials, And Methods:...
8.
Thol F, Weissinger E, Krauter J, Wagner K, Damm F, Wichmann M, et al.
Haematologica . 2010 May; 95(10):1668-74. PMID: 20494930
Background: Myelodysplastic syndromes are a heterogeneous group of hematopoietic stem cell disorders with a high propensity to transform into acute myeloid leukemia. Heterozygous missense mutations in IDH1 at position R132...
9.
Reins J, Mossner M, Neumann M, Platzbecker U, Schumann C, Thiel E, et al.
Leuk Res . 2010 May; 34(12):1610-6. PMID: 20471677
Secreted frizzled related protein 1 (SFRP1) is an extracellular antagonist of the Wnt signalling pathway that plays an important role in the pathogenesis of solid tumours and haematopoietic malignancies. SFRP1...
10.
Nowak-Gottl U, Ahlke E, Fleischhack G, Schwabe D, Schobess R, Schumann C, et al.
Blood . 2003 Jan; 101(7):2529-33. PMID: 12517808
Alterations in hemostasis leading to symptomatic thromboembolism have been observed in patients with acute lymphoblastic leukemia (ALL) receiving Escherichia coli asparaginase (CASP) combined with steroids. Moreover, hereditary prothrombotic risk factors...