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Christian Simader

Explore the profile of Christian Simader including associated specialties, affiliations and a list of published articles. Areas
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Articles 67
Citations 4118
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Recent Articles
1.
Karst S, Deak G, Gerendas B, Waldstein S, Lammer J, Simader C, et al.
JAMA Ophthalmol . 2018 Mar; 136(4):315-321. PMID: 29494727
Importance: Anti-vascular endothelial growth factor treatment is the first-line therapy in the treatment of center-involving diabetic macular edema. Data on capillary perfusion changes under repeated treatment in a possibly compromised...
2.
Haj Najeeb B, Simader C, Deak G, Vass C, Gamper J, Montuoro A, et al.
Invest Ophthalmol Vis Sci . 2017 Aug; 58(10):3986-3990. PMID: 28796876
Purpose: To determine the distribution of leakage on fluorescein angiography (FA) and explore the clinically protective role of astrocytes against damage to the inner blood retinal barrier (iBRB) in diabetic...
3.
Gerendas B, Prager S, Deak G, Simader C, Lammer J, Waldstein S, et al.
Br J Ophthalmol . 2017 Jul; 102(2):195-203. PMID: 28724636
Background/aims: The objective is to identify imaging biomarkers in optical coherence tomography predicting functional/anatomical outcomes in diabetic macular oedema (DMO). Methods: The presented study is a post hoc analysis of...
4.
Podkowinski D, Sharian Varnousfaderani E, Simader C, Bogunovic H, Philip A, Gerendas B, et al.
J Ophthalmol . 2017 Jun; 2017:8148047. PMID: 28630764
Background And Objective: To determine optimal image averaging settings for Spectralis optical coherence tomography (OCT) in patients with and without cataract. Study Design/material And Methods: In a prospective study, the...
5.
Heier J, Korobelnik J, Brown D, Schmidt-Erfurth U, Do D, Midena E, et al.
Ophthalmology . 2016 Sep; 123(11):2376-2385. PMID: 27651226
Purpose: To compare efficacy and safety of intravitreal aflibercept injection (IAI) with macular laser photocoagulation for diabetic macular edema (DME) over 3 years. Design: Two similarly designed phase 3 trials:...
6.
Wu J, Philip A, Podkowinski D, Gerendas B, Langs G, Simader C, et al.
J Ophthalmol . 2016 Sep; 2016:3898750. PMID: 27579177
Development of image analysis and machine learning methods for segmentation of clinically significant pathology in retinal spectral-domain optical coherence tomography (SD-OCT), used in disease detection and prediction, is limited due...
7.
Varnousfaderani E, Wu J, Vogl W, Philip A, Montuoro A, Leitner R, et al.
Comput Methods Programs Biomed . 2016 May; 130:93-105. PMID: 27208525
Background And Objectives: The lack of benchmark data in computational ophthalmology contributes to the challenging task of applying disease assessment and evaluate performance of machine learning based methods on retinal...
8.
Waldstein S, Simader C, Staurenghi G, Chong N, Mitchell P, Jaffe G, et al.
Ophthalmology . 2016 May; 123(7):1521-9. PMID: 27157149
Purpose: To compare the efficacy of intravitreal aflibercept and ranibizumab on the exudative activity of neovascular age-related macular degeneration (nAMD) using optical coherence tomography (OCT) and to correlate morphologic findings...
9.
Philip A, Gerendas B, Zhang L, Faatz H, Podkowinski D, Bogunovic H, et al.
Br J Ophthalmol . 2016 Jan; 100(10):1372-6. PMID: 26769670
Background/aims: The purpose of the study was to create a standardised protocol for choroidal thickness measurements and to determine whether choroidal thickness measurements made on images obtained by spectral domain...
10.
Waldstein S, Philip A, Leitner R, Simader C, Langs G, Gerendas B, et al.
JAMA Ophthalmol . 2015 Dec; 134(2):182-90. PMID: 26661463
Importance: Robust and sensitive imaging biomarkers for visual function are an unmet medical need in the management of neovascular age-related macular degeneration. Objective: To determine the correlation of 3-dimensionally quantified...