Christian R Eckmann
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Explore the profile of Christian R Eckmann including associated specialties, affiliations and a list of published articles.
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32
Citations
3275
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Recent Articles
1.
Oyewale T, Eckmann C
Sci Adv
. 2022 Oct;
8(41):eabn0897.
PMID: 36240265
How the germ line achieves a clean transition from maternal to zygotic gene expression control is a fundamental problem in sexually reproducing organisms. Whereas several mechanisms terminate the maternal program...
2.
Nousch M, Yeroslaviz A, Eckmann C
Nucleic Acids Res
. 2019 Sep;
47(20):10881-10893.
PMID: 31511882
RNA-modifying enzymes targeting mRNA poly(A) tails are universal regulators of post-transcriptional gene expression programs. Current data suggest that an RNA-binding protein (RBP) directed tug-of-war between tail shortening and re-elongating enzymes...
3.
Kisielnicka E, Minasaki R, Eckmann C
Proc Natl Acad Sci U S A
. 2018 Mar;
115(12):E2772-E2781.
PMID: 29496961
RNA-binding proteins (RBPs) are important regulators of gene expression programs, especially during gametogenesis. How the abundance of particular RBPs is restricted to defined stages of meiosis remains largely elusive. Here,...
4.
Nousch M, Minasaki R, Eckmann C
RNA
. 2017 May;
23(8):1180-1187.
PMID: 28490506
The role of many enzymes extends beyond their dedicated catalytic activity by fulfilling important cellular functions in a catalysis-independent fashion. In this aspect, little is known about 3'-end RNA-modifying enzymes...
5.
Saha S, Weber C, Nousch M, Adame-Arana O, Hoege C, Hein M, et al.
Cell
. 2016 Sep;
166(6):1572-1584.e16.
PMID: 27594427
P granules are non-membrane-bound RNA-protein compartments that are involved in germline development in C. elegans. They are liquids that condense at one end of the embryo by localized phase separation,...
6.
Nakel K, Bonneau F, Basquin C, Habermann B, Eckmann C, Conti E
RNA
. 2016 Jun;
22(8):1139-45.
PMID: 27288313
Cytoplasmic polyadenylation drives the translational activation of specific mRNAs in early metazoan development and is performed by distinct complexes that share the same catalytic poly(A)-polymerase subunit, GLD-2. The activity and...
7.
Millonigg S, Minasaki R, Nousch M, Novak J, Eckmann C
PLoS Genet
. 2016 Feb;
12(2):e1005862.
PMID: 26859383
No abstract available.
8.
Nousch M, Eckmann C
Worm
. 2015 Oct;
4(3):e1042644.
PMID: 26430565
Adult tissue maintenance is achieved through a tightly controlled equilibrium of 2 opposing cell fates: stem cell proliferation and differentiation. In recent years, the germ line emerged as a powerful...
9.
Nakel K, Bonneau F, Eckmann C, Conti E
Proc Natl Acad Sci U S A
. 2015 Jul;
112(28):8614-9.
PMID: 26124149
The Caenorhabditis elegans germ-line development defective (GLD)-2-GLD-3 complex up-regulates the expression of genes required for meiotic progression. GLD-2-GLD-3 acts by extending the short poly(A) tail of germ-line-specific mRNAs, switching them...
10.
Elbaum-Garfinkle S, Kim Y, Szczepaniak K, Chen C, Eckmann C, Myong S, et al.
Proc Natl Acad Sci U S A
. 2015 May;
112(23):7189-94.
PMID: 26015579
P granules and other RNA/protein bodies are membrane-less organelles that may assemble by intracellular phase separation, similar to the condensation of water vapor into droplets. However, the molecular driving forces...