Christian Magnac
Overview
Explore the profile of Christian Magnac including associated specialties, affiliations and a list of published articles.
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Articles
8
Citations
99
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Recent Articles
1.
Vuillier F, Dumas G, Magnac C, Prevost M, Lalanne A, Oppezzo P, et al.
Blood
. 2004 Dec;
105(7):2933-40.
PMID: 15591116
Low levels of B-cell-receptor (BCR) expression are the hallmark of tumoral B lymphocytes in B-cell chronic lymphocytic leukemia (B-CLL). These cells also respond inadequately to stimulation through the BCR. This...
2.
Oppezzo P, Dumas G, Lalanne A, Payelle-Brogard B, Magnac C, Pritsch O, et al.
Blood
. 2004 Nov;
105(6):2495-503.
PMID: 15561888
Activation-induced cytidine deaminase (AID) is key to initiating somatic hypermutation (SHM) and class switch recombination (CSR), but its mode of action and regulation remains unclear. Since Pax-5 and Id-2 transcription...
3.
Vasconcelos Y, Davi F, Levy V, Oppezzo P, Magnac C, Michel A, et al.
J Clin Oncol
. 2003 Oct;
21(21):3928-32.
PMID: 14581416
Purpose: Rai's and Binet's staging systems have contributed significantly to the identification of major prognostic groups in chronic lymphocytic leukemia (CLL), though they fail to accurately predict disease progression at...
4.
Vuillier F, Maloum K, Thomas E, Magnac C, Dumas G, Payelle-Brogard B, et al.
Br J Haematol
. 2003 Jan;
120(2):243-50.
PMID: 12542481
Idiotypic structures of immunoglobulins from malignant B cells constitute tumour-specific antigens, though the function of immunoglobulin-specific CD8+ T cells in disease control and rejection remains unclear. We have studied five...
5.
Oppezzo P, Vuillier F, Vasconcelos Y, Dumas G, Magnac C, Payelle-Brogard B, et al.
Blood
. 2003 Jan;
101(10):4029-32.
PMID: 12521993
In B cells, somatic hypermutation (SHM) and class switch recombination (CSR) depend on the activation-induced cytidine deaminase (AID) gene product, although the precise mode of action of AID remains unknown....
6.
Maloum K, Sutton L, Baudet S, Laurent C, Bonnemye P, Magnac C, et al.
Br J Haematol
. 2002 Dec;
119(4):970-5.
PMID: 12472575
We describe a new flow-cytometric analysis using quadruple labelling with anti-CD19, CD20, CD5, CD79b monoclonal antibodies and sequential gating. We determined a novel criteria defined by BCD5+CD79b-/low/total BCD5+ cells ratio...
7.
Theodorou I, Abel L, Mauro F, Duprey B, Magnac C, Payelle-Brogard B, et al.
Br J Haematol
. 2002 Nov;
119(3):713-5.
PMID: 12437649
Recently, linkage analysis of a series of familial chronic lymphocytic leukaemia (CLL) showed that affected sibling pairs did not share common major histocompatibilty complex haplotypes. We analysed Class I and...
8.
Payelle-Brogard B, Magnac C, Alcover A, Roux P, Dighiero G
Br J Haematol
. 2002 Aug;
118(4):976-85.
PMID: 12199775
B-cell chronic lymphocytic leukaemia (B-CLL) characteristically displays low amounts of B-cell receptor (BCR), which mainly consists of the heterodimer CD79a/CD79b bound non-covalently with the surface immunoglobulin (SIg). This heterodimer is...