Christian Lajaunie
Overview
Explore the profile of Christian Lajaunie including associated specialties, affiliations and a list of published articles.
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7
Citations
237
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Recent Articles
1.
Guyon L, Lajaunie C, Fer F, Bhajun R, Sulpice E, Pinna G, et al.
Sci Rep
. 2015 Sep;
5:14221.
PMID: 26382112
Phenotypic screening monitors phenotypic changes induced by perturbations, including those generated by drugs or RNA interference. Currently-used methods for scoring screen hits have proven to be problematic, particularly when applied...
2.
Bhajun R, Guyon L, Pitaval A, Sulpice E, Combe S, Obeid P, et al.
Sci Rep
. 2015 Feb;
5:8336.
PMID: 25673565
MiRNAs are key regulators of gene expression. By binding to many genes, they create a complex network of gene co-regulation. Here, using a network-based approach, we identified miRNA hub groups...
3.
Pauwels E, Lajaunie C, Vert J
BMC Syst Biol
. 2014 Sep;
8(1):102.
PMID: 25256134
BackgroundDynamical models used in systems biology involve unknown kinetic parameters. Setting these parameters is a bottleneck in many modeling projects. This motivates the estimation of these parameters from empirical data....
4.
Filhol O, Ciais D, Lajaunie C, Charbonnier P, Foveau N, Vert J, et al.
PLoS One
. 2012 Nov;
7(10):e48057.
PMID: 23118925
Chemically synthesized small interfering RNA (siRNA) is a widespread molecular tool used to knock down genes in mammalian cells. However, designing potent siRNA remains challenging. Among tools predicting siRNA efficacy,...
5.
Lemaire F, Mandon C, Reboud J, Papine A, Angulo J, Pointu H, et al.
PLoS One
. 2007 Jan;
2(1):e163.
PMID: 17235363
Background: Improved chemical hazard management such as REACH policy objective as well as drug ADMETOX prediction, while limiting the extent of animal testing, requires the development of increasingly high throughput...
6.
Vert J, Foveau N, Lajaunie C, Vandenbrouck Y
BMC Bioinformatics
. 2006 Dec;
7:520.
PMID: 17137497
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional study and new drug...
7.
Carrat F, Luong J, Lao H, Salle A, Lajaunie C, Wackernagel H
BMC Med
. 2006 Oct;
4:26.
PMID: 17059593
Background: With an influenza pandemic seemingly imminent, we constructed a model simulating the spread of influenza within the community, in order to test the impact of various interventions. Methods: The...