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Christian A Schmidt

Explore the profile of Christian A Schmidt including associated specialties, affiliations and a list of published articles. Areas
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Articles 63
Citations 1122
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Recent Articles
1.
Susemihl A, Geist N, Grabarczyk P, Schmidt C, Delcea M, Schulig L
Proteins . 2025 Feb; PMID: 39976228
The transcription factor B Cell Lymphoma/Leukemia 11B (BCL11B) exerts a bi-directional function in cancer, with its role as an emerging therapeutic target in cancer treatment being particularly intriguing. BCL11B knockouts...
2.
Forkel H, Grabarczyk P, Depke M, Troschke-Meurer S, Simm S, Hammer E, et al.
Oncoimmunology . 2022 Dec; 11(1):2148850. PMID: 36507091
BCL11B, an essential transcription factor for thymopoiesis, regulates also vital processes in post-thymic lymphocytes. Increased expression of BCL11B was recently correlated with the maturation of NK cells, whereas reduced BCL11B...
3.
Spath C, Schonau M, Gaubert S, Neumann T, Schmidt C, Heidel F, et al.
Ann Hematol . 2022 Jun; 101(9):2111-2112. PMID: 35715705
No abstract available.
4.
Przybylski G, Korsak D, Izykowska K, Nowicka K, Zalewski T, Tubacka M, et al.
Int J Mol Sci . 2022 May; 23(9). PMID: 35563322
The B-cell CLL/lymphoma 11B gene (BCL11B) plays a crucial role in T-cell development, but its role in T-cell malignancies is still unclear. To study its role in the development of...
5.
Susemihl A, Nagel F, Grabarczyk P, Schmidt C, Delcea M
Molecules . 2021 Dec; 26(24). PMID: 34946663
Zinc finger proteins play pivotal roles in health and disease and exert critical functions in various cellular processes. A majority of zinc finger proteins bind DNA and act as transcription...
6.
Kruger W, Hirt C, Basara N, Sayer H, Behre G, Fischer T, et al.
Ann Hematol . 2021 Apr; 100(6):1569-1577. PMID: 33829299
Mantle cell lymphoma (MCL) is a non-Hodgkin's lymphoma with an often aggressive course, incurable by chemotherapy. Consolidation with high-dose therapy and autologous stem cell transplantation (autoSCT) has a low transplant-related...
7.
Schulig L, Grabarczyk P, Geist N, Delin M, Forkel H, Kulke M, et al.
Int J Mol Sci . 2021 Apr; 22(7). PMID: 33807484
Transcription factors play a crucial role in regulating biological processes such as cell growth, differentiation, organ development and cellular signaling. Within this group, proteins equipped with zinc finger motifs (ZFs)...
8.
Kruger W, Buchhold B, Nonnenberg D, Neumann T, Schneidewind L, Schmidt C
Am J Hosp Palliat Care . 2021 Jan; 38(10):1212-1217. PMID: 33433238
Allogeneic stem cell transplantation (alloSCT) is a curative therapy for otherwise fatal diseases, however it is associated with a considerable morbidity and mortality. In consequence, it can be assumed that...
9.
Schneidewind L, Neumann T, Kruger W, Hakenberg O, Schmidt C
J Cell Mol Med . 2020 Jun; 24(16):9097-9100. PMID: 32588533
The BK polyomavirus (BKPyV) has pathogenic relevance especially in immunocompromised patients. No causal therapy has been established yet. Therefore, new therapeutic targets need to be identified in experimental studies. A...
10.
Knop S, Engelhardt M, Liebisch P, Meisner C, Holler E, Metzner B, et al.
Leukemia . 2019 Aug; 33(11):2710-2719. PMID: 31462732
This phase 3 trial compared tandem autologous stem cell transplantation (autoSCT) versus autoSCT followed by reduced-intensity conditioning allogeneic stem cell transplantation (auto/alloSCT) in patients with newly diagnosed multiple myeloma (MM)...