Christi A Walter
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Explore the profile of Christi A Walter including associated specialties, affiliations and a list of published articles.
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39
Citations
663
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Recent Articles
1.
Jaiswal A, Kim H, Scharer O, Sharma N, Williamson E, Srinivasan G, et al.
NAR Cancer
. 2023 Jan;
5(1):zcac044.
PMID: 36683914
Unrepaired oxidatively-stressed replication forks can lead to chromosomal instability and neoplastic transformation or cell death. To meet these challenges cells have evolved a robust mechanism to repair oxidative genomic DNA...
2.
Boswell M, Lu Y, Boswell W, Savage M, Hildreth K, Salinas R, et al.
Genes (Basel)
. 2019 Apr;
10(4).
PMID: 30987199
Fluorescent light (FL) has been utilized for ≈60 years and has become a common artificial light source under which animals, including humans, spend increasing amounts of time. Although the solar...
3.
Kohutova A, Raska J, Kruta M, Seneklova M, Barta T, Fojtik P, et al.
FASEB J
. 2019 Feb;
33(6):6778-6788.
PMID: 30807703
Maintenance of human embryonic stem cells (hESCs) with stable genome is important for their future use in cell replacement therapy and disease modeling. Our understanding of the mechanisms maintaining genomic...
4.
Zavadil J, Herzig M, Hildreth K, Foroushani A, Boswell W, Walter R, et al.
Mol Carcinog
. 2018 Oct;
58(3):309-320.
PMID: 30365185
Hepatocellular carcinoma (HCC) remains a deadly cancer, underscoring the need for relevant preclinical models. Male C3HeB/FeJ mice model spontaneous HCC with some hepatocarcinogenesis susceptibility loci corresponding to syntenic regions of...
5.
Cooper D, Chen I, Hernandez C, Wang Y, Walter C, McCarrey J
Stem Cell Res
. 2017 Jan;
19:113-117.
PMID: 28129601
Pluripotent cells have been reported to exhibit lower frequencies of point mutations and higher levels of DNA repair than differentiated cells. This predicts that pluripotent cells are less susceptible to...
6.
Dong Q, Gao H, Shi Y, Zhang F, Gu X, Wu A, et al.
Aging (Albany NY)
. 2016 Nov;
8(11):2754-2776.
PMID: 27852980
Breast cancer incidence increases during aging, yet the mechanism of age-associated mammary tumorigenesis is unclear. Mammary stem cells are believed to play an important role in breast tumorigenesis, but how...
7.
Herzig M, Zavadil J, Street K, Hildreth K, Drinkwater N, Reddick T, et al.
Cancer Prev Res (Phila)
. 2015 Dec;
9(3):245-52.
PMID: 26667451
Hepatocellular carcinoma is increasingly important in the United States as the incidence rate rose over the last 30 years. C3HeB/FeJ mice serve as a unique model to study hepatocellular carcinoma...
8.
Sanchez J, Reddick T, Perez M, Centonze V, Mitra S, Izumi T, et al.
Mutat Res
. 2015 Jul;
779:124-33.
PMID: 26201249
Increased paternal age is associated with a greater risk of producing children with genetic disorders originating from de novo germline mutations. Mice mimic the human condition by displaying an age-associated...
9.
Cooper D, Walter C, McCarrey J
Stem Cell Res
. 2014 Dec;
13(3 Pt A):508-19.
PMID: 25451711
The Disposable Soma Theory holds that genetic integrity will be maintained at more pristine levels in germ cells than in somatic cells because of the unique role germ cells play...
10.
Cheng Z, Zhou T, Merchant A, Prihoda T, Wickes B, Xu G, et al.
J Vis Exp
. 2014 Mar;
(84):e50752.
PMID: 24637843
In recent years, it has become apparent that genomic instability is tightly related to many developmental disorders, cancers, and aging. Given that stem cells are responsible for ensuring tissue homeostasis...