Christelle Bolea
Overview
Explore the profile of Christelle Bolea including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
120
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0
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Recent Articles
1.
Epping-Jordan M, Girard F, Bessis A, Mutel V, Bolea C, Derouet F, et al.
Cells
. 2023 Apr;
12(7).
PMID: 37048075
Parkinson's disease (PD) patients suffer not only from the primary motor symptoms of the disease but also from a range of non-motor symptoms (NMS) that cause disability and low quality...
2.
Kannampalli P, Poli S, Bolea C, Sengupta J
Neuropharmacology
. 2017 Aug;
126:1-11.
PMID: 28823612
Therapeutic use of GABA receptor agonists for conditions like chronic abdominal pain, overactive bladder (OAB) and gastroesophageal reflux disease (GERD) is severely affected by poor blood-brain barrier permeability and potential...
3.
Kalinichev M, Le Poul E, Bolea C, Girard F, Campo B, Fonsi M, et al.
J Pharmacol Exp Ther
. 2014 Jun;
350(3):495-505.
PMID: 24947466
There is growing evidence that activation of metabotropic glutamate receptor 4 (mGlu4) leads to anxiolytic- and antipsychotic-like efficacy in rodent models, yet its relevance to depression-like reactivity remains unclear. Here,...
4.
Le Poul E, Bolea C, Girard F, Poli S, Charvin D, Campo B, et al.
J Pharmacol Exp Ther
. 2012 Jul;
343(1):167-77.
PMID: 22787118
Positive allosteric modulators (PAMs) of metabotropic glutamate receptor 4 (mGluR4) have been proposed as a novel therapeutic approach for the treatment of Parkinson's disease. However, evaluation of this proposal has...
5.
Cid J, Duvey G, Cluzeau P, Nhem V, Macary K, Raux A, et al.
ACS Chem Neurosci
. 2012 Jul;
1(12):788-95.
PMID: 22778815
A series of 1,5-disubstituted pyridones was identified as positive allosteric modulators (PAMs) of the metabotropic glutamate receptor 2 (mGluR2) via high throughput screening (HTS). Subsequent SAR exploration led to the...
6.
Rocher J, Bonnet B, Bolea C, Lutjens R, Le Poul E, Poli S, et al.
Curr Top Med Chem
. 2011 Jan;
11(6):680-95.
PMID: 21261592
Allosteric modulators of metabotropic glutamate receptors (mGluR) subtypes 1-8 have been shown to offer a valid way to develop small molecule non aminoacid-like therapeutics that can be administered orally and...
7.
Gayet A, Bolea C, Andersson P
Org Biomol Chem
. 2004 Jul;
2(13):1887-93.
PMID: 15227541
A new class of N,S-containing chiral compounds based on the camphor scaffold have been synthesised and evaluated as chiral catalysts in the transfer hydrogenation of acetophenone. The best results were...