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Christa M Cobbaert

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Articles 132
Citations 1009
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Recent Articles
1.
Kruijt M, Cobbaert C, Ruhaak L
Mass Spectrom Rev . 2025 Mar; PMID: 40088190
Our healthcare system provides reactive sick-care, treating patients after symptoms have appeared by prescription of generic and often suboptimal therapy. This strategy brings along high costs and high pressure which...
2.
van Rijn C, Abdoel C, Baktawar S, Herbel P, Junschke A, Bryant M, et al.
Clin Chem Lab Med . 2025 Mar; PMID: 40025747
Objectives: Detailed technical instructions have been made for harmonization of the prothrombin time (PT) test using the manual tilt tube technique (MTT). The MTT has been proposed as the reference...
3.
Schwartz G, Szarek M, Reijnders E, Jukema J, Bhatt D, Bittner V, et al.
Eur J Prev Cardiol . 2025 Feb; PMID: 39921475
Aims: Apolipoprotein (Apo) C3 has been associated with incident coronary heart disease and major adverse cardiovascular events (MACE). Whether ApoC3 levels predict risk in patients with acute coronary syndrome (ACS)...
4.
Schwartz G, Szarek M, Jukema J, Cobbaert C, Reijnders E, Bittner V, et al.
Diabetes Care . 2025 Feb; PMID: 39913634
Objective: Previous genetic and clinical analyses have associated lower lipoprotein(a) and LDL cholesterol (LDL-C) with greater risk of new-onset type 2 diabetes (NOD). However, PCSK9 inhibitors such as alirocumab lower...
5.
Buchta C, De la Salle B, Marrington R, Aburto Almonacid A, Albarede S, Badrick T, et al.
Clin Chem Lab Med . 2025 Jan; PMID: 39753240
External quality assessment (EQA) enhances patient safety through the evaluation of the quality of laboratory-based and point of care testing. Regulatory agencies and accreditation organizations utilize the results and the...
6.
Buchta C, Marrington R, De la Salle B, Albarede S, Albe X, Badrick T, et al.
Clin Chem Lab Med . 2025 Jan; PMID: 39753204
Providers of external quality assessment (EQA) programs evaluate data or information obtained and reported by participant laboratories using their routine procedures to examine properties or measurands in samples provided for...
7.
Miida T, Hirayama S, Fukushima Y, Hori A, Ito S, Hinata M, et al.
J Atheroscler Thromb . 2024 Nov; PMID: 39505497
Aim: Lipoprotein (a) [Lp(a)] is a well-established risk factor for cardiovascular disease independent of low-density lipoprotein-cholesterol (LDL-C). The Lp(a) concentrations were inconsistent between the immunoassays. This study aimed to investigate...
8.
Henricks L, Romijn F, Cobbaert C
Clin Chem Lab Med . 2024 Oct; 63(3):645-652. PMID: 39479776
Objectives: As high-sensitivity cardiac troponin T (hs-cTnT) is making the transition from diagnostic to prognostic use, a long-term stability study of 5th generation hs-cTnT according to EFLM CRESS recommendations was...
9.
van der Burgt Y, Romijn F, Treep M, Ruhaak L, Cobbaert C
Clin Chem Lab Med . 2024 Oct; 63(4):780-789. PMID: 39450666
Objectives: Quantitative protein mass spectrometry (MS) is ideally suited for precision diagnostics and for reference standardization of protein analytes. At the Leiden Apolipoprotein Reference Laboratory we apply MS strategies to...
10.
Kruijt M, de la Morena-Barrio M, Corral J, Cobbaert C, Ruhaak L
J Thromb Haemost . 2024 Oct; 23(1):210-221. PMID: 39423957
Background: Although P5 (preventive, personalized, predictive, participatory, psychocognitive) medicine and patient-focused healthcare are gaining ground in various healthcare areas, the diagnosis of antithrombin deficiency (ATD) is still based on crude...