Chris Q Doe
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Explore the profile of Chris Q Doe including associated specialties, affiliations and a list of published articles.
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Articles
122
Citations
6570
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Recent Articles
1.
Dillon N, Doe C
Development
. 2024 Dec;
151(24).
PMID: 39620972
The generation of neuronal diversity is important for brain function, but how diversity is generated is incompletely understood. We used the development of the Drosophila central complex (CX) to address...
2.
Pollington H, Doe C
bioRxiv
. 2024 Oct;
PMID: 39416181
Interneuron diversity within the central nervous system (CNS) is essential for proper circuit assembly. Functional interneurons must integrate multiple features, including combinatorial transcription factor (TF) expression, axon/dendrite morphology, and connectivity...
3.
Doe C, Thor S
Development
. 2024 May;
151(11).
PMID: 38819456
Drosophila nervous system development progresses through a series of well-characterized steps in which homeodomain transcription factors (HDTFs) play key roles during most, if not all, phases. Strikingly, although some HDTFs...
4.
Dillon N, Manning L, Hirono K, Doe C
Development
. 2024 Jan;
151(3).
PMID: 38230563
An unanswered question in neurobiology is how are diverse neuron cell types generated from a small number of neural stem cells? In the Drosophila larval central brain, there are eight...
5.
Xu C, Ramos T, Marshall O, Doe C
Elife
. 2024 Jan;
12.
PMID: 38193901
Notch signaling is an evolutionarily conserved pathway for specifying binary neuronal fates, yet how it specifies different fates in different contexts remains elusive. In our accompanying paper, using the lamina...
6.
Xu C, Ramos T, Rogers E, Reiser M, Doe C
Elife
. 2024 Jan;
12.
PMID: 38180023
How our brain generates diverse neuron types that assemble into precise neural circuits remains unclear. Using lamina neuron types (L1-L5), we show that the primary homeodomain transcription factor (HDTF) brain-specific...
7.
Munroe J, Doe C
Neural Dev
. 2023 Nov;
18(1):9.
PMID: 38031099
The generation of neuronal diversity remains incompletely understood. In Drosophila, the central brain is populated by neural stem cells derived from progenitors called neuroblasts (NBs). There are two types of...
8.
Dillon N, Manning L, Hirono K, Doe C
bioRxiv
. 2023 Nov;
PMID: 37961302
An open question in neurobiology is how diverse neuron cell types are generated from a small number of neural stem cells. In the larval central brain, there are eight bilateral...
9.
Munroe J, Syed M, Doe C
PLoS One
. 2022 Dec;
17(12):e0272177.
PMID: 36520944
Stem cells must balance proliferation and quiescence, with excess proliferation favoring tumor formation, and premature quiescence preventing proper organogenesis. Drosophila brain neuroblasts are a model for investigating neural stem cell...
10.
Heckman E, Doe C
Elife
. 2022 Nov;
11.
PMID: 36448675
The organization of neural circuits determines nervous system function. Variability can arise during neural circuit development (e.g. neurite morphology, axon/dendrite position). To ensure robust nervous system function, mechanisms must exist...