Chris M McNair
Overview
Explore the profile of Chris M McNair including associated specialties, affiliations and a list of published articles.
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Articles
3
Citations
60
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0
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Recent Articles
1.
DiNatale A, Kaur R, Qian C, Zhang J, Marchioli M, Ipe D, et al.
Oncogene
. 2022 Jan;
41(9):1337-1351.
PMID: 34999735
Metastasis-initiating cells (MICs) display stem cell-like features, cause metastatic recurrences and defy chemotherapy, which leads to patients' demise. Here we show that prostate and breast cancer patients harbor contingents of...
2.
Mandigo A, Shafi A, McCann J, Yuan W, Laufer T, Bogdan D, et al.
Cancer Res
. 2021 Oct;
82(2):221-234.
PMID: 34625422
The retinoblastoma tumor suppressor (RB) is a critical regulator of E2F-dependent transcription, controlling a multitude of protumorigenic networks including but not limited to cell-cycle control. Here, genome-wide assessment of E2F1...
3.
The circadian cryptochrome, CRY1, is a pro-tumorigenic factor that rhythmically modulates DNA repair
Shafi A, McNair C, McCann J, Alshalalfa M, Shostak A, Severson T, et al.
Nat Commun
. 2021 Jan;
12(1):401.
PMID: 33452241
Mechanisms regulating DNA repair processes remain incompletely defined. Here, the circadian factor CRY1, an evolutionally conserved transcriptional coregulator, is identified as a tumor specific regulator of DNA repair. Key findings...