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Chris K Grant

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Citations 220
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Recent Articles
1.
Murphy B, Castillo D, Neely N, Kol A, Brostoff T, Grant C, et al.
Viruses . 2024 Mar; 16(3). PMID: 38543827
Feline infectious peritonitis (FIP) is a multisystemic, generally lethal immuno-inflammatory disease of domestic cats caused by an infection with a genetic variant of feline coronavirus, referred to as the FIP...
2.
Murphy B, Castillo D, Cook S, Eckstrand C, Evans S, Sparger E, et al.
Viruses . 2023 Aug; 15(8). PMID: 37632117
Feline immunodeficiency virus (FIV) is a lentivirus in the family Retroviridae that infects domestic cats resulting in an immunodeficiency disease featuring a progressive and profound decline in multiple sets of...
3.
Ngo M, Arnal M, Sumi R, Kawasaki J, Miyake A, Grant C, et al.
J Virol . 2019 Sep; 93(24). PMID: 31534037
Endogenous retroviruses (ERVs) of domestic cats (ERV-DCs) are one of the youngest feline ERV groups in domestic cats (); some members are replication competent (ERV-DC10, ERV-DC18, and ERV-DC14), produce the...
4.
Roukaerts I, Grant C, Theuns S, Christiaens I, Acar D, Van Bockstael S, et al.
Virus Res . 2016 Nov; 227:249-260. PMID: 27836726
Env and Gag are key components of the FIV virion that are targeted to the plasma membrane for virion assembly. They are both important stimulators and targets of anti-FIV immunity....
5.
Flies A, Mansfield L, Flies E, Grant C, Holekamp K
Funct Ecol . 2016 Nov; 30(9):1549-1557. PMID: 27833242
Social rank can profoundly affect many aspects of mammalian reproduction and stress physiology, but little is known about how immune function is affected by rank and other socio-ecological factors in...
6.
Kaye S, Wang W, Miller C, McLuckie A, Beatty J, Grant C, et al.
ILAR J . 2016 Apr; 57(1):24-33. PMID: 27034392
Feline immunodeficiency virus (FIV) is a naturally occurring lentivirus of domestic and nondomestic feline species. Infection in domestic cats leads to immune dysfunction via mechanisms similar to those caused by...
7.
Flies A, Mansfield L, Grant C, Weldele M, Holekamp K
PLoS One . 2015 Oct; 10(10):e0137679. PMID: 26444876
Evolutionary processes have shaped the vertebrate immune system over time, but proximal mechanisms control the onset, duration, and intensity of immune responses. Based on testing of the hygiene hypothesis, it...
8.
Hu Q, Fink E, Grant C, Elder J
PLoS One . 2014 Dec; 9(12):e115252. PMID: 25521480
Heparan sulfate proteoglycans (HSPG) can act as binding receptors for certain laboratory-adapted (TCA) strains of feline immunodeficiency virus (FIV) and human immunodeficiency virus (HIV). Heparin, a soluble heparin sulfate (HS),...
9.
Flies A, Grant C, Mansfield L, Smith E, Weldele M, Holekamp K
Vet Immunol Immunopathol . 2011 Dec; 145(1-2):110-9. PMID: 22173276
Animals that hunt and scavenge are often exposed to a broad array of pathogens. Theory predicts the immune systems of animals specialized for scavenging should have been molded by selective...
10.
Hu Q, Fink E, Hong Y, Wang C, Grant C, Elder J
PLoS One . 2010 May; 5(5):e10689. PMID: 20502526
The chemokine receptor CXCR4 is shared by primary and laboratory-adapted strains of feline immunodeficiency virus (FIV) for viral entry. Our previous studies implicated a contiguous nine-amino-acid region of the V3...