Chris Hawkey
Overview
Explore the profile of Chris Hawkey including associated specialties, affiliations and a list of published articles.
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22
Citations
3486
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Recent Articles
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Hawkey C, Avery A, Coupland C, Crooks C, Dumbleton J, Hobbs F, et al.
Lancet
. 2022 Nov;
400(10363):1597-1606.
PMID: 36335970
Background: Peptic ulcers in patients receiving aspirin are associated with Helicobacter pylori infection. We aimed to investigate whether H pylori eradication would protect against aspirin-associated ulcer bleeding. Methods: We conducted...
3.
Snowden J, Hawkey C, Hind D, Swaby L, Mellor K, Emsley R, et al.
BMC Gastroenterol
. 2019 Jun;
19(1):82.
PMID: 31151436
Background: Intestinal inflammation in Crohn's disease (CD) is caused by mucosal immune system reactivity to luminal antigen and results in debilitating symptoms, reduced quality of life, impaired work productivity and...
4.
Walker J, Hutchison P, Ge J, Zhao D, Wang Y, Rothwell P, et al.
Ecancermedicalscience
. 2018 Mar;
12:813.
PMID: 29515654
Acetylsalicylic acid was first synthesised by Dr FeIix Hoffman on 10th August 1897 and Aspirin was born. It quickly became the best-known pain killer in the world and in the...
5.
Snowden J, Panes J, Alexander T, Allez M, Ardizzone S, Dierickx D, et al.
J Crohns Colitis
. 2018 Jan;
12(4):476-488.
PMID: 29325112
Despite the major recent progress in the treatment of Crohn's disease [CD], there is a subset of patients in whom the disease runs an aggressive course with progressive tissue damage...
6.
Britton J, Gadeke L, Lovat L, Hamdy S, Hawkey C, Mclaughlin J, et al.
Lancet Gastroenterol Hepatol
. 2017 Sep;
2(11):824-831.
PMID: 28867477
The incidence of gastro-oesophageal reflux disease and Barrett's oesophagus is increasing. Barrett's oesophagus is the main precursor to oesophageal adenocarcinoma, which has a poor prognosis. In view of the vast...
7.
Mowat C, Arnott I, Cahill A, Smith M, Ahmad T, Subramanian S, et al.
Lancet Gastroenterol Hepatol
. 2017 Apr;
1(4):273-282.
PMID: 28404197
Background: Up to 60% of patients with Crohn's disease need intestinal resection within the first 10 years of diagnosis, and postoperative recurrence is common. We investigated whether mercaptopurine can prevent...
8.
Luo Y, de Lange K, Jostins L, Moutsianas L, Randall J, Kennedy N, et al.
Nat Genet
. 2017 Jan;
49(2):186-192.
PMID: 28067910
To further resolve the genetic architecture of the inflammatory bowel diseases ulcerative colitis and Crohn's disease, we sequenced the whole genomes of 4,280 patients at low coverage and compared them...
9.
de Lange K, Moutsianas L, Lee J, Lamb C, Luo Y, Kennedy N, et al.
Nat Genet
. 2017 Jan;
49(2):256-261.
PMID: 28067908
Genetic association studies have identified 215 risk loci for inflammatory bowel disease, thereby uncovering fundamental aspects of its molecular biology. We performed a genome-wide association study of 25,305 individuals and...
10.
Mackenzie I, Ford I, Walker A, Hawkey C, Begg A, Avery A, et al.
BMJ Open
. 2016 Sep;
6(9):e013774.
PMID: 27609859
Introduction: Ischaemic heart disease (IHD) is one of the most common causes of death in the UK and treatment of patients with IHD costs the National Health System (NHS) billions...