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Chris H Compton

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Articles 7
Citations 321
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Recent Articles
1.
Mannino D, Weng S, Germain G, Boudreau J, Tardif-Samson A, Forero-Schwanhaeuser S, et al.
Adv Ther . 2024 Dec; 42(2):1131-1146. PMID: 39731707
Introduction: Chronic obstructive pulmonary disease (COPD) is associated with exacerbations which can reduce quality of life and increase mortality. Single-inhaler triple therapy (SITT) is recommended for maintenance treatment of COPD...
2.
Ritchie A, Donaldson G, Hoffman E, Allinson J, Bloom C, Bolton C, et al.
Am J Respir Crit Care Med . 2024 Jan; 209(10):1208-1218. PMID: 38175920
Chronic obstructive pulmonary disease (COPD) due to tobacco smoking commonly presents when extensive lung damage has occurred. We hypothesized that structural change would be detected early in the natural history...
3.
Donaldson G, Ritchie A, Calverley P, Vestbo J, Fageras M, de la Hoz A, et al.
ERJ Open Res . 2021 Nov; 7(4). PMID: 34820444
https://bit.ly/3laMsmi.
4.
Hartley B, Barnes N, Lettis S, Compton C, Papi A, Jones P
Respir Res . 2020 Jan; 21(1):5. PMID: 31907054
Background: Patients with chronic obstructive pulmonary disease (COPD) are at risk of exacerbations and pneumonia; how the risk factors interact is unclear. Methods: This post-hoc, pooled analysis included studies of...
5.
Whittaker H, Mullerova H, Jarvis D, Barnes N, Jones P, Compton C, et al.
Int J Chron Obstruct Pulmon Dis . 2019 Jun; 14:1063-1073. PMID: 31213788
Inhaled corticosteroid (ICS)-containing medications slow rate of decline of FEV. Blood eosinophil (EOS) levels are associated with the degree of exacerbation reduction with ICS. We investigated whether FEV decline differs...
6.
Shaw D, Sousa A, Fowler S, Fleming L, Roberts G, Corfield J, et al.
Eur Respir J . 2015 Sep; 46(5):1308-21. PMID: 26357963
U-BIOPRED is a European Union consortium of 20 academic institutions, 11 pharmaceutical companies and six patient organisations with the objective of improving the understanding of asthma disease mechanisms using a...
7.
Bel E, Sousa A, Fleming L, Bush A, Chung K, Versnel J, et al.
Thorax . 2010 Nov; 66(10):910-7. PMID: 21106547
Patients with severe refractory asthma pose a major healthcare problem. Over the last decade it has become increasingly clear that, for the development of new targeted therapies, there is an...