Chris B Schaffer
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Explore the profile of Chris B Schaffer including associated specialties, affiliations and a list of published articles.
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88
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4290
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Recent Articles
1.
Isaacson M, Chang H, Berkowitz L, Zirkel R, Park Y, Hu D, et al.
Nat Methods
. 2024 Dec;
22(2):380-385.
PMID: 39668209
Small-animal virtual reality (VR) systems have become invaluable tools in neuroscience for studying complex behavior during head-fixed neural recording, but they lag behind commercial human VR systems in terms of...
2.
Lieberman S, Rivera D, Morton R, Hingorani A, Southard T, Johnson L, et al.
Adv Sci (Weinh)
. 2024 May;
11(29):e2300747.
PMID: 38810146
In partial onset epilepsy, seizures arise focally in the brain and often propagate. Patients frequently become refractory to medical management, leaving neurosurgery, which can cause neurologic deficits, as a primary...
3.
Cheng Y, Lett K, Xu C, Schaffer C
bioRxiv
. 2024 Apr;
PMID: 38617307
Nonlinear optical microscopy enables non-invasive imaging in scattering samples with cellular resolution. The spinal cord connects the brain with the periphery and governs fundamental behaviors such as locomotion and somatosensation....
4.
Rivera D, Buglione A, Ray S, Schaffer C
PLoS One
. 2024 Mar;
19(3):e0299047.
PMID: 38437201
Small animal studies in biomedical research often require anesthesia to reduce pain or stress experienced by research animals and to minimize motion artifact during imaging or other measurements. Anesthetized animals...
5.
Rivera D, Schaffer C
Biomed Opt Express
. 2023 Oct;
14(8):3950-3967.
PMID: 37799691
Laser speckle contrast imaging (LSCI) is a widefield imaging technique that enables high spatiotemporal resolution measurement of blood flow. Laser coherence, optical aberrations, and static scattering effects restrict LSCI to...
6.
Zielinski K, Sui S, Pabit S, Rivera D, Wang T, Hu Q, et al.
Sci Adv
. 2023 Sep;
9(39):eadj3509.
PMID: 37756398
RNA macromolecules, like proteins, fold to assume shapes that are intimately connected to their broadly recognized biological functions; however, because of their high charge and dynamic nature, RNA structures are...
7.
Zielinski K, Sui S, Pabit S, Rivera D, Wang T, Hu Q, et al.
bioRxiv
. 2023 Jun;
PMID: 37292849
RNA macromolecules, like proteins, fold to assume shapes that are intimately connected to their broadly recognized biological functions; however, because of their high charge and dynamic nature, RNA structures are...
8.
Sidorenko P, Buttolph M, Mejooli M, Eom C, Schaffer C, Wise F
Biomed Opt Express
. 2023 May;
14(5):2324-2332.
PMID: 37206123
Two-photon excited fluorescence microscopy is a widely-employed imaging technique that enables the noninvasive study of biological specimens in three dimensions with sub-micrometer resolution. Here, we report an assessment of a...
9.
Rivera D, Schaffer C
bioRxiv
. 2023 May;
PMID: 37131699
Laser speckle contrast imaging (LSCI) is a widefield imaging technique that enables high spatiotemporal resolution measurement of blood flow. Laser coherence, optical aberrations, and static scattering effects restrict LSCI to...
10.
Ruiz-Uribe N, Bracko O, Swallow M, Omurzakov A, Dash S, Uchida H, et al.
bioRxiv
. 2023 Feb;
PMID: 36824768
Introduction: In this study, we explore the role of oxidative stress produced by NOX2-containing NADPH oxidase as a molecular mechanism causing capillary stalling and cerebral blood flow deficits in the...