Chongzhuo Zhu
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Explore the profile of Chongzhuo Zhu including associated specialties, affiliations and a list of published articles.
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6
Citations
1276
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Recent Articles
1.
Ma Q, Zhang W, Zhu C, Liu J, Chen Q
Cardiovasc Res
. 2018 Dec;
115(11):1672-1679.
PMID: 30576423
Aims: AKT kinase is vital for regulating signal transduction in platelet aggregation. We previously found that mitochondrial protein FUNDC2 mediates phosphoinositide 3-kinase (PI3K)/phosphatidylinositol-3,4,5-trisphosphate (PIP3)-dependent AKT phosphorylation and regulates platelet apoptosis....
2.
Ma Q, Zhu C, Zhang W, Ta N, Zhang R, Liu L, et al.
Cell Death Differ
. 2018 May;
26(2):321-331.
PMID: 29786068
Platelets undergo apoptosis in response to a variety of stimuli in the circulation. Mitochondria in platelets are essential for their apoptosis. Specifically, pro-survival protein BCL-x on mitochondria is the key...
3.
Zhang W, Ren H, Xu C, Zhu C, Wu H, Liu D, et al.
Elife
. 2016 Dec;
5.
PMID: 27995894
Mitochondrial dysfunction underlies many prevalent diseases including heart disease arising from acute ischemia/reperfusion (I/R) injury. Here, we demonstrate that mitophagy, which selectively removes damaged or unwanted mitochondria, regulated mitochondrial quality...
4.
Chen M, Chen Z, Wang Y, Tan Z, Zhu C, Li Y, et al.
Autophagy
. 2016 Apr;
12(4):689-702.
PMID: 27050458
Mitochondrial fragmentation due to imbalanced fission and fusion of mitochondria is a prerequisite for mitophagy, however, the exact "coupling" of mitochondrial dynamics and mitophagy remains unclear. We have previously identified...
5.
Wu H, Xue D, Chen G, Han Z, Huang L, Zhu C, et al.
Autophagy
. 2014 Aug;
10(10):1712-25.
PMID: 25126723
Receptor-mediated mitophagy is one of the major mechanisms of mitochondrial quality control essential for cell survival. We previously have identified FUNDC1 as a mitophagy receptor for selectively removing damaged mitochondria...
6.
Liu L, Feng D, Chen G, Chen M, Zheng Q, Song P, et al.
Nat Cell Biol
. 2012 Jan;
14(2):177-85.
PMID: 22267086
Accumulating evidence has shown that dysfunctional mitochondria can be selectively removed by mitophagy. Dysregulation of mitophagy is implicated in the development of neurodegenerative disease and metabolic disorders. How individual mitochondria...