Chong Wing Yung
Overview
Explore the profile of Chong Wing Yung including associated specialties, affiliations and a list of published articles.
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10
Citations
776
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Recent Articles
1.
Ryan D, Taussig D, Steinfeld I, Phadnis S, Lunstad B, Singh M, et al.
Nucleic Acids Res
. 2017 Dec;
46(2):792-803.
PMID: 29216382
CRISPR systems have emerged as transformative tools for altering genomes in living cells with unprecedented ease, inspiring keen interest in increasing their specificity for perfectly matched targets. We have developed...
2.
Kang J, Super M, Yung C, Cooper R, Domansky K, Graveline A, et al.
Nat Med
. 2014 Sep;
20(10):1211-6.
PMID: 25216635
Here we describe a blood-cleansing device for sepsis therapy inspired by the spleen, which can continuously remove pathogens and toxins from blood without first identifying the infectious agent. Blood flowing...
3.
Mammoto A, Mammoto T, Kanapathipillai M, Yung C, Jiang E, Jiang A, et al.
Nat Commun
. 2013 Apr;
4:1759.
PMID: 23612300
Increased vascular permeability contributes to many diseases, including acute respiratory distress syndrome, cancer and inflammation. Most past work on vascular barrier function has focused on soluble regulators, such as tumour-necrosis...
4.
Mammoto T, Mammoto A, Torisawa Y, Tat T, Gibbs A, Derda R, et al.
Dev Cell
. 2011 Sep;
21(4):758-69.
PMID: 21924961
Mesenchymal condensation is critical for organogenesis, yet little is known about how this process is controlled. Here we show that Fgf8 and Sema3f, produced by early dental epithelium, respectively, attract...
5.
Yung C, Bentley W, Barbari T
J Biomed Mater Res A
. 2010 Aug;
95(1):25-32.
PMID: 20740597
In designing an implantable cell encapsulation construct to continuously deliver therapeutic proteins to a patient, it is critical that the biomaterial be compatible with the encapsulated cells, as well as...
6.
Fainaru O, Almog N, Yung C, Nakai K, Montoya-Zavala M, Abdollahi A, et al.
FASEB J
. 2009 Dec;
24(5):1411-8.
PMID: 20008545
Dendritic cells (DCs)--immunomodulatory cells that initiate adaptive immune responses--have recently been shown to exert proangiogenic effects when infiltrating the tumor microenvironment. As tumors that escape immune surveillance inhibit DC maturation,...
7.
Yung C, Fiering J, Mueller A, Ingber D
Lab Chip
. 2009 Apr;
9(9):1171-7.
PMID: 19370233
Sepsis is a lethal disease caused by a systemic microbial infection that spreads via the bloodstream to overwhelm the body's defenses. Current therapeutic approaches are often suboptimal, in part, because...
8.
Mammoto A, Connor K, Mammoto T, Yung C, Huh D, Aderman C, et al.
Nature
. 2009 Feb;
457(7233):1103-8.
PMID: 19242469
Angiogenesis is controlled by physical interactions between cells and extracellular matrix as well as soluble angiogenic factors, such as VEGF. However, the mechanism by which mechanical signals integrate with other...
9.
Yung C, Barbari T, Bentley W
Biotechnol Bioeng
. 2006 Aug;
95(5):938-45.
PMID: 16933326
Cell encapsulation has been used to treat diabetes, amyotrophic lateral sclerosis, and other chronic ailments by the secretion of therapeutic proteins in vivo. Detection of these proteins typically requires invasive...
10.
Yung C, Barbari T, Bentley W
Metab Eng
. 2006 Jun;
8(5):483-90.
PMID: 16793304
In the encapsulated environment of biohybrid artificial organs, cells often encounter a deficiency in oxygen, which lead to apoptosis, necrosis, and lost of productivity. Two vectors with constitutive CMV promoters...