Chloe B Fishman
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Explore the profile of Chloe B Fishman including associated specialties, affiliations and a list of published articles.
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7
Citations
53
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Recent Articles
1.
Fishman C, Crawford K, Bhattarai-Kline S, Poola D, Zhang K, Gonzalez-Delgado A, et al.
Nat Biotechnol
. 2024 Sep;
PMID: 39237706
Bacteriophage genome editing can enhance the efficacy of phages to eliminate pathogenic bacteria in patients and in the environment. However, current methods for editing phage genomes require laborious screening, counterselection...
2.
Roberts C, Fishman C, Banh D, Marraffini L
bioRxiv
. 2024 Aug;
PMID: 39131286
Toll/interleukin-1 receptor (TIR) domains are present in immune systems that protect prokaryotes from viral (phage) attack. In response to infection, TIRs can produce a cyclic adenosine diphosphate-ribose (ADPR) signaling molecule,...
3.
Gonzalez-Delgado A, Lopez S, Rojas-Montero M, Fishman C, Shipman S
Nat Chem Biol
. 2024 Jul;
20(11):1482-1492.
PMID: 38982310
During recent years, the use of libraries-scale genomic manipulations scaffolded on CRISPR guide RNAs have been transformative. However, these existing approaches are typically multiplexed across genomes. Unfortunately, building cells with...
4.
Gonzalez-Delgado A, Lopez S, Rojas-Montero M, Fishman C, Shipman S
bioRxiv
. 2023 Jul;
PMID: 37503029
Our understanding of genomics is limited by the scale of our genomic technologies. While libraries of genomic manipulations scaffolded on CRISPR gRNAs have been transformative, these existing approaches are typically...
5.
Fishman C, Crawford K, Bhattarai-Kline S, Zhang K, Gonzalez-Delgado A, Shipman S
bioRxiv
. 2023 Mar;
PMID: 36993281
Bacteriophages, which naturally shape bacterial communities, can be co-opted as a biological technology to help eliminate pathogenic bacteria from our bodies and food supply. Phage genome editing is a critical...
6.
Bhattarai-Kline S, Lear S, Fishman C, Lopez S, Lockshin E, Schubert M, et al.
Nature
. 2022 Jul;
608(7921):217-225.
PMID: 35896746
Biological processes depend on the differential expression of genes over time, but methods to make physical recordings of these processes are limited. Here we report a molecular system for making...
7.
Palka C, Fishman C, Bhattarai-Kline S, Myers S, Shipman S
Nucleic Acids Res
. 2022 Mar;
50(6):3490-3504.
PMID: 35293583
Retrons are bacterial retroelements that produce single-stranded, reverse-transcribed DNA (RT-DNA) that is a critical part of a newly discovered phage defense system. Short retron RT-DNAs are produced from larger, structured...