Chintan Parekh
Overview
Explore the profile of Chintan Parekh including associated specialties, affiliations and a list of published articles.
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Articles
28
Citations
545
Followers
0
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Recent Articles
1.
Jambon S, Sun J, Barman S, Muthugounder S, Bito X, Shadfar A, et al.
Blood Cancer Discov
. 2024 Dec;
6(1):55-72.
PMID: 39624992
Our study demonstrates the use of "IF-THEN" SynNotch-gated CAR-T cells targeting CD33 and CD123 in AML reduces off-tumor toxicity. This strategy enhances T-cell phenotype, improves expansion, preserves HSPCs, and mitigates...
2.
Comparison of human pluripotent stem cell differentiation protocols to generate neuroblastoma tumors
Cheng B, Fang W, Pastor S, March A, Porras T, Wu H, et al.
Sci Rep
. 2024 Oct;
14(1):23050.
PMID: 39367051
Neuroblastoma is the most common pediatric extracranial solid tumor and is derived from trunk neural crest cells (tNCC) and its progenitor sympathoadrenal (SA) cells. While human pluripotent stem cell (PSC)...
3.
Parker R, Le J, Villa M, Luong A, Lin T, Lee Y, et al.
Int J Cancer
. 2024 Jul;
155(12):2190-2200.
PMID: 39005114
Little is known about the efficacy of COVID-19 vaccines during acute lymphoblastic leukemia therapy (ALL); data for COVID-19 vaccine immune responses in pediatric leukemia remain sparse. We conducted a single...
4.
Ma J, Morimoto K, Pulsipher M, Parekh C
JCO Precis Oncol
. 2023 Jun;
7:e2200693.
PMID: 37315262
No abstract available.
5.
Doan A, Huang H, Hadar A, Malvar J, Rushing T, Raca G, et al.
Br J Haematol
. 2023 May;
202(1):e3-e6.
PMID: 37129267
No abstract available.
6.
Parker R, Le J, Doan A, Aguayo-Hiraldo P, Pannaraj P, Rushing T, et al.
Int J Cancer
. 2022 Jul;
151(11):1913-1924.
PMID: 35793239
Pediatric oncology patients are at risk for poor outcomes with respiratory viral infections. Outcome data for COVID-19 in children and young adults with cancer are needed; data are sparse for...
7.
Ruan Y, Kim H, Ogana H, Wan Z, Hurwitz S, Nichols C, et al.
Front Oncol
. 2021 Dec;
11:766888.
PMID: 34926269
The PI3K/Akt pathway-and in particular PI3Kδ-is known for its role in drug resistant B-cell acute lymphoblastic leukemia (B-ALL) and it is often upregulated in refractory or relapsed B-ALL. Myc proteins...
8.
Sun V, Sharpley M, Kaczor-Urbanowicz K, Chang P, Montel-Hagen A, Lopez S, et al.
Front Immunol
. 2021 Aug;
12:716661.
PMID: 34394122
Although metabolic pathways have been shown to control differentiation and activation in peripheral T cells, metabolic studies on thymic T cell development are still lacking, especially in human tissue. In...
9.
Gaynon P, Parekh C
Pediatr Blood Cancer
. 2021 Jul;
68(10):e29238.
PMID: 34302711
No abstract available.
10.
Le J, Ha V, Luong A, Parekh C
STAR Protoc
. 2020 Oct;
1(2):100090.
PMID: 33111122
Single cell RNA sequencing of human thymic cells is dependent on isolation of highly pure and viable cell populations. This protocol describes the isolation of CD34 progenitor and more differentiated...